DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpr76Bc and CPR141

DIOPT Version :9

Sequence 1:	NP_001097644.1	Gene:	Cpr76Bc / 40122	FlyBaseID:	FBgn0036880	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_565332.2	Gene:	CPR141 / 3290257	VectorBaseID:	AGAP006867	Length:	392	Species:	Anopheles gambiae

Alignment Length:	430	Identity:	142/430 - (33%)
Similarity:	201/430 - (46%)	Gaps:	121/430 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 DETMEYAPHYEHQGYAFSYGVKDLHTGDVKSQWESRDGDGVKGHYSVLEPDGSIRTVHYTADAKK 106
            |....|||.|.|..|:|||||||||:||||||||:||...|||||||:|||||||.|.||||:|.
Mosquito    25 DSLHAYAPEYAHPAYSFSYGVKDLHSGDVKSQWETRDDGIVKGHYSVVEPDGSIREVDYTADSKT 89

  Fly   107 GFNAIVKTVGANSHPITESPEGSNQ-----VNDDTSQSKINHYSKDQEHIVLSSDIKPLKRPIED 166
            ||||:|||.|.|:||:.: |...::     .::..|||||||:||.|:|::||||:...::.|.:
Mosquito    90 GFNAVVKTHGPNAHPVRD-PHDQHEHKTHYYDEHHSQSKINHFSKGQDHLILSSDLPHHEKDIAE 153

  Fly   167 LTHSHPKVPSLIEIKPHARIKQVPMDMDPGIRDRLQQARDTYYKQIAAAHKLEDYSQKLQPTYAV 231
            :......:||::|:|||..:::      |.:..:..:...|.:         :.||.
Mosquito   154 IGEKKRPIPSILELKPHVNLEK------PLVAYKHYEPPKTIF---------QHYSH-------- 195

  Fly   232 QEGDWKAVIVNEPKEYRPHYTTGSPAHSHFY------DHYKPKEIPHNYIHKPSV-------PQQ 283
                         .|.:|||.|....|||.:      |.:..:......:.|||:       |..
Mosquito   196 -------------DELKPHYVTVETEHSHKHYVSDSADFFSEQLDSDKDLFKPSIRIEEVKAPDL 247

  Fly   284 SLHTSFSPSKPRINIPES----------------ISNHIH-----QKKVVH-------------- 313
            |.....||.....::.||                .:||:.     ||..||
Mosquito   248 SKLKPISPDVDFSHLSESDLGPYYTKDSYRPFAQYNNHVSHPVTLQKAKVHAIQVDSKPKKNLLK 312

  Fly   314 --TTPGLKHYK----YKGVSKSYSRPDYSSYFHRKPKKLRPQHPKQKPRAHRPENSGPVLFPKSL 372
              ||||||::.    ||..::..:||||:|||              |.:..|...:||||
Mosquito   313 PLTTPGLKNFATPSVYKFAARGPARPDYASYF--------------KSKGSRQARTGPVL----- 358

  Fly   373 EDEFEDFEEDEQGAASATLVQNMVRKDKKHMVPMYAGGHS 412
                  |..|||..||..:||:|:.:.....||:||..::
Mosquito   359 ------FHPDEQKRASQRMVQSMLSRQHSRNVPVYAKNYA 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpr76Bc	NP_001097644.1	Chitin_bind_4	56..108	CDD:278791	40/51 (78%)
CPR141	XP_565332.2	Chitin_bind_4	39..91	CDD:278791	40/51 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	108	1.000	Domainoid score	I12516
eggNOG	1	0.900	-	-		E1_2EWEZ
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80798
Inparanoid	1	1.050	208	1.000	Inparanoid score	I6101
OMA	1	1.010	-	-		QHG26164
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0020076
OrthoInspector	1	1.000	-	-		oto105758
Panther	1	1.100	-	-	LDO	PTHR12236
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X15695
TreeFam	1	0.960	-	-
	12	11.930