DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9451 and CG6656

DIOPT Version :9

Sequence 1:	NP_001262050.1	Gene:	CG9451 / 40118	FlyBaseID:	FBgn0036876	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_650991.1	Gene:	CG6656 / 42576	FlyBaseID:	FBgn0038912	Length:	395	Species:	Drosophila melanogaster

Alignment Length:	362	Identity:	123/362 - (33%)
Similarity:	206/362 - (56%)	Gaps:	18/362 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 AKDSVSNSTLKLVHVLFRHGPRTPVSTYPNDPYINETYEPFGWGALTNGAKVELYKIGKQLRQRY 111
            :.|......|:::.:|||||.:.|...||.||:....::. |.||||....::.|.:|:.||.||
  Fly    33 SNDEQGLRNLRMISILFRHGAKNPSGFYPLDPHAAHDWQG-GMGALTPKGSLQAYNLGRNLRMRY 96

  Fly   112 KDFLP--AYYQPDAIRAQSSESPRTLMSMQMVLAGLFPP-ENTPMEWNQL-LNWQPIPIVMEPEE 172
            ...||  :.|....:...||.:.|.:||.|.||||:.|| ||.    |.| :.|||:.:......
  Fly    97 YRLLPPNSLYTQQQVNVLSSAAERCVMSAQSVLAGMMPPLENK----NVLPIPWQPVAVNTLSRN 157

  Fly   173 TDVHIRMKAPCPRYDESVLEVIEL--PEVKKLHAESSDLLRELTTHTGLNITHAHDVTNVFITLL 235
            .|:.:..|.||.:||..:.::.:.  ||::||:.::.:|.:.||.:||.||::..||..::.||.
  Fly   158 EDILLAQKKPCLKYDHILQKLYKSPPPELQKLNEDNMELYKLLTKNTGKNISNVLDVELLYGTLK 222

  Fly   236 CEQTFGLQLPSWTNDYFPEKMLPLAEKSYVYDAYTTEQRKMKGGFFVELLLKQMQDRISGALKPA 300
            .|:...|.||.||.:.:||::.||||:||:....|...:::|||.|:..:|.:||::....|.|
  Fly   223 TEEEANLVLPDWTENIYPEEIRPLAERSYMLFTETNLMKRIKGGAFLTDILNKMQNKRKRNLNP- 286

  Fly   301 NRKMFLSCGHDWTITNVLSALNVWE--AQMPRFSSLIAFELHQNP--QTGEYFLE-IYFQNDPHK 360
            :||:||..|||.|:.||:::|.:.:  .::|.::|.:|||||.:.  ..|::.:: :|:.|...|
  Fly   287 DRKIFLYSGHDVTLVNVMNSLGILDQTTKLPEYASALAFELHHSKSFSDGDFEVKLVYYYNSEDK 351

  Fly   361 EPQQLQIPGCEKQCPIGKLLELTKDIIPDAPYAELCK 397
            .|::|.||.|:..|.:.:.....|.::.| .|.|.|:
  Fly   352 FPKELTIPNCDAPCSLTQFEASVKALLLD-NYDETCE 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9451	NP_001262050.1	HP_HAP_like	55..355	CDD:132717	109/310 (35%)
CG6656	NP_650991.1	HP_HAP_like	41..344	CDD:132717	108/308 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4084
eggNOG	1	0.900	-	-		E1_KOG3720
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	64	1.000	Inparanoid score	I1972
Isobase	1	0.950	-	0	Normalized mean entropy	S7717
OMA	1	1.010	-	-		QHG28676
OrthoDB	1	1.010	-	-		D1221585at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11567
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4294
	9	8.930