DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brv1 and CG42685

DIOPT Version :9

Sequence 1:	NP_649116.1	Gene:	brv1 / 40116	FlyBaseID:	FBgn0036874	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	NP_609717.5	Gene:	CG42685 / 34854	FlyBaseID:	FBgn0261571	Length:	1609	Species:	Drosophila melanogaster

Alignment Length:	398	Identity:	74/398 - (18%)
Similarity:	131/398 - (32%)	Gaps:	152/398 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 TGKLFLVYFFMALAF----FDELLYFN-----TEATELLFQCNHGDAFGLLSVGDVPDIYFFVVS 183
            |..:.|:.|| ||.|    |..||:.|     .:..|...||   ||    |||.....:.....
  Fly  1311 TFNMILMIFF-ALLFLLLVFKFLLHLNIISAYLKNPEFRLQC---DA----SVGKSDQSFVSGSE 1367

  Fly   184 SLVLAFTDGKNTSGGAPWIHAEGTRLLGVVRLRQLRTESNRLGLSLPVFTERDFSESWTLPYERV 248
            .|::..|.|:..:|                      |.||                  ...|.:.
  Fly  1368 ILLVIVTGGQEFAG----------------------TTSN------------------VKFYLKS 1392

  Fly   249 PYTDK--YWPIYTPWLPSVSVARDNLLMGINHVGHMF-------------NYPESKGYKVLLSDT 298
            |:..:  |.....|..|  .:.|::.:..:...||::             .||......:.:.|.
  Fly  1393 PHRQQTSYQITQDPGHP--KLLRNSTIKIMVPRGHIYIPTRLALRLVPNGRYPSWYCRSITVVDL 1455

  Fly   299 RHKSLKIIDYLMKKNWLDANTTALFMDFSLYNADANTFTVCTLWVEKFPYQYPDGHTRIESHTFV 363
            :   ||:....:.::|::..:...||. |.|                |.|   ..::|...:|:.
  Fly  1456 K---LKVQQLFLVESWIEGGSHIQFMR-SKY----------------FTY---GNYSRYPKYTWC 1497

  Fly   364 EQLREFTKFGMLMVFVFVVTWLQFTKAFFLKVWY------DPRQLKT------------LWVQVD 410
            ::.|...:            .|.|:       ||      .|.|.|.            :|:...
  Fly  1498 KRFRSRAE------------QLYFS-------WYLINAITGPSQSKVGGIIMNQFERTCVWICKT 1543

  Fly   411 AMIVA-LSLVVG--MIMSVRDNLVQKMIKSVEIAVVVDFLDFREPAQLAYLEDVVTGLAV----- 467
            |:.:| ::|..|  .:.|:::...:.:..|:::.:|| .|.|     .|:|    .|||:
  Fly  1544 AITLAFVTLYFGKHTVSSIQEETRENVDNSLKVHLVV-MLGF-----FAFL----IGLAIHVLFE 1598

  Fly   468 ALVTMRLW 475
            .::...||
  Fly  1599 VIILRWLW 1606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brv1	NP_649116.1	PKD_channel	165..591	CDD:285288	59/352 (17%)
CG42685	NP_609717.5	REJ	411..753	CDD:307914
CG42685	NP_609717.5	PLAT	1367..1480	CDD:238061	23/158 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276906at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010