Protein Alignment brv1 and brv3

DIOPT Version :9

• Sequence 1: NP_649116.1
• Gene: brv1 / 40116
• FlyBaseID: FBgn0036874
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_001284831.1
• Gene: brv3 / 31246
• FlyBaseID: FBgn0040333
• Length: 750
• Species: Drosophila melanogaster
• Alignment Length: 736
• Identity: 280/736 - (38%)
• Similarity: 445/736 - (60%)
• Gaps: 22/736 - (2%)

  Fly     3 KKFSNIIFYLTLIIIAICVACIWMFSGFRHEYGKFNMILVAFLAVTLLQILIFTPIKFTIMSLDA 67
            ||....:|.:|:.||..|:.||.:|:||:||..||..:||:.:.|.:.|.||..||||.|:|:|.
  Fly     4 KKTHWAMFAITVGIIIGCMICIAVFAGFQHEDVKFKTMLVSIVIVLIFQFLIGDPIKFVILSIDR 68

  Fly    68 AFWP--AHQAPE-TPDENANVDTFMDNLRLRLRTLRSELMITERHRNERVNLKYRLITEELWLTG 129
            |.||  .:..|. ..||....:...|.|:.||...|:.||:|.|:||.::|.:|::|..:|::.|
  Fly    69 ALWPPRIYIPPRCDKDEMDEKEERRDFLKQRLINKRANLMLTSRYRNYKLNDQYKMIAHDLFIYG 133

  Fly   130 KLFLVYFFMALAFFDELLYFNTEATELLFQCNHGDAFGLLSVGDVPDIYFFVVSSLVLAFTDGKN 194
            ..||....:.|...|:.||.||.....||..||.|..||..|..:..::.|:.|:|||||.....
  Fly   134 PYFLCLMCLVLVTRDQTLYHNTRIITDLFMYNHTDYTGLQEVYFLNQLFDFIESTLVLAFNSNST 198

  Fly   195 TSGGAPWIHAEGTRLLGVVRLRQLRTESNRLGLSLPVFTERDFSESWTLPYERVPYTDKYWPIYT 259
            .||...|.|||.:.||||:||||||..:.::||..|.|::..:...|.|||.::.|:||||.||.
  Fly   199 ESGSPGWAHAEQSVLLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYSDKYWRIYE 263

  Fly   260 PWLPSVSVA---RDNLLMGINHVGHMFNYPESKGYKVLLSDTRHKSLKIIDYLMKKNWLDANTTA 321
            ||:| :.:.   .|.|||..:|||.:.:|||..||..||:.:...|:|:||||.:.:||..||:|
  Fly   264 PWIP-IKMGFEFLDALLMNFDHVGSLNSYPELAGYVSLLARSAANSMKVIDYLSENHWLTLNTSA 327

  Fly   322 LFMDFSLYNADANTFTVCTLWVEKFPYQ--YPDGHTRIESHTFVEQLREFTKFGMLMVFVFVVTW 384
            :|:||:|||.|.|.|::|||.|||.|:.  .||  .:::|...:|.:.:....|:|.:.::|:.:
  Fly   328 VFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPD--VQVDSAKLLENVDQMPYTGLLALLIYVLVF 390

  Fly   385 LQFTKAFFLKVWYDPRQLKTLWVQVDAMIVALSLVVGMIMSVRDNLVQKMIKSVEIAVVVDFLDF 449
            :||.:...:|:||:|..||::|.::|..|..::::|.:::.:|::||..|:|.||.|..::|:||
  Fly   391 IQFAQTLAVKLWYEPHLLKSVWNKLDLFIFMVNVLVVVLVVLRESLVASMMKKVEGASKMEFIDF 455

  Fly   450 REPAQLAYLEDVVTGLAVALVTMRLWKVLQFSATFQLFTKTIAMAWDALLCTFVITVIFIIAIGI 514
            |.|:::..|..:..|..:.:.|:|||:||||::.|:|||:|:.:||.|:..|.:..|||:|....
  Fly   456 RRPSRMHQLTTITIGFLICITTLRLWRVLQFASVFKLFTRTLYLAWSAVASTAIAIVIFLIGFCF 520

  Fly   515 ATVTINGNYTSNFRDFPKGIVTVTCFAFGYTNLVYPPDIFYGGEWLGILLYTIMGFVVKYMLINL 579
            |.|||||||:|||....|.:|...|::||::..|.|.::|:||:|||||.|.::.||:..:|||:
  Fly   521 AVVTINGNYSSNFNKLVKSMVMCMCYSFGFSAQVKPSELFHGGKWLGILCYGVLAFVIIVLLINV 585

  Fly   580 IVSMMRDQMASVKADRDKKVRQRITFWQFLRVEYAHFINYIVKVFHCQKGYQRKNRTVAQNIQRK 644
            .||::.|.....|..||.:...||||::||.||::..:....|:...::.|.|..||||:|:.||
  Fly   586 FVSLINDYFTVAKTIRDSERENRITFFEFLVVEFSGVLGRFRKLPCWRRNYVRNGRTVAENVSRK 650

  Fly   645 LNS---NELKRRKTKISSIYSETIYVMPIDKDLEQMKYRERIERTFTLAAILHTQMELMERLMFG 706
            |:|   ..|.||:.:....:..    .|:..:...::|::|.::...:..||:.|:.|:...:|
  Fly   651 LDSMDRQRLMRRRLRQGRHHVS----RPVSAEDALLEYKDRGDKMVNVHYILNIQLTLIRMFLF- 710

  Fly   707 DEEGNLPSLDQEDEQVPETEE 727
            ||....|   ||.::.||.::
  Fly   711 DEYVEWP---QEQQKQPEAQD 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brv1	NP_649116.1	PKD_channel	165..591	CDD:285288	175/430 (41%)
brv3	NP_001284831.1	PKD_channel	170..595	CDD:285288	175/427 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445324
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46093
OrthoDB	1	1.010	-	-		D1276906at2759
OrthoFinder	1	1.000	-	-		FOG0016837
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10877
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.860