Protein Alignment brv1 and Pkdrej

DIOPT Version :9

• Sequence 1: NP_649116.1
• Gene: brv1 / 40116
• FlyBaseID: FBgn0036874
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_001128338.1
• Gene: Pkdrej / 300124
• RGDID: 1306587
• Length: 2121
• Species: Rattus norvegicus
• Alignment Length: 689
• Identity: 125/689 - (18%)
• Similarity: 246/689 - (35%)
• Gaps: 160/689 - (23%)

  Fly    14 LIIIAICVACIW--------------MFSGFRHEYGKFNMILVAFLAVTLLQILIFTPIKFTIMS 64
            :|:...||...|              :|.|..:.|.|....|.|........:.:..|....:.|
  Rat  1438 IILPRRCVYIAWFLVFATSGVSSFFIVFYGLTYGYDKSVEWLFASFCSFCQSVFLVQPCHILLRS 1502

  Fly    65 LDAAFWPAHQAPETPDENANVDTFMDNLRLRLRTLRSELMITERHRNERVNLK----YRLITEE- 124
            ......|.:      .:|.:..:......:||:.|:.....||:...:...::    |:.|||:
  Rat  1503 GTRMHRPKY------CKNLSWSSKYHYTEIRLQELKMTPEETEQLHEDMAYIRSLSIYQPITEDK 1561

  Fly   125 ---------LWLTGKLFLVYFFMALAFFDELLYFNTEATELLFQCNHGDAF------------GL 168
                     :.....|||.|......|...||.       |:|...|.|:|            .|
  Rat  1562 IQIFRRKNRIRKRSFLFLSYLVTHFIFLTLLLL-------LIFPLRHNDSFYYNQFVRHRFSMDL 1619

  Fly   169 LSVGDVPDIYFFVVSSLVLAFTDGKNTSGGAPWIHAEGTRLLGVVRLRQLRTE-SNRLGLSLPVF 232
            .:|..:.|||.::....:....:.|:.:    ::....:::||:..:||:|.: ||:..|....|
  Rat  1620 ATVVKLGDIYAWLNGVFLPLLHNDKSPT----FLPDSSSKILGLPLMRQVRAKPSNKTCLLAKKF 1680

  Fly   233 TE--------------------RDFSESWTLPYERVPYTDK------YWPIYTPWL-PSVSVARD 270
            .:                    |.:...|....:|  ..||      |.|....|: .|..|
  Rat  1681 AQSRIAGELHCHPQYGIDPEDTRHYPGVWNKAGKR--SIDKTSNGFTYKPPGRKWVYYSYGV--- 1740

  Fly   271 NLLMGINHVG----HMFNYPESKGYKVLLSDTRHKSLKIIDYLMKKNWLDANTTALFMDFSLYNA 331
                 :|..|    ..:.:||.:.:.   |..|.|.|:      .|||||..|.|:.::.:..|.
  Rat  1741 -----LNTYGSGGYEFYFFPEQQMFN---STLRLKELE------GKNWLDELTWAVIVELTTLNP 1791

  Fly   332 DANTFTVCTLWV--EKFP----------YQYPDGHTRIESHTFVEQLREFTKFGMLMVFVFVVTW 384
            |  |..:|::.|  |..|          |.:|              |.:|.......::::|..
  Rat  1792 D--TSLMCSISVVFEVSPLGVVNSSLSVYSFP--------------LADFNSRSSAEIYLYVAI- 1839

  Fly   385 LQFTKAFFLKVWYDPRQLKTLWVQ--VDAMIVALSLVVGMIMSVRDNLVQKMIKSVEIAVVVD-- 445
            |.|..|:.:...|...|.:..:::  .:.:..:|..:..:::.:   ..||.:.:.::..:.:
  Rat  1840 LIFFCAYVVDEGYIIMQERASYIRSMYNLLNFSLKCMFALLIVL---FFQKHLLATKLVRLYNTD 1901

  Fly   446 ---FLDFREPAQLAYLEDVVTGLAVALVTMRLWKVLQFSATFQLFTKTIAMAWDALLCTFVITVI 507
               |:.|...:::.:...::....:.|..::..:..:|....:|..|||..|:..:..|.::..|
  Rat  1902 PEAFIPFHAVSRVDHFMRIILAFLLFLTILKTLRYSRFFYNVRLAQKTIQAAFPGICHTALVVSI 1966

  Fly   508 F---IIAIGIATVTINGNYTSNFRDFPKGIVTVTCFAFGYTNLVYPPDIFYGGEWLGILLYTIMG 569
            :   .:|.|   ..:.|.:..|:    ..::..|...|.|....:....|.|.:.||:|..:...
  Rat  1967 YSFMYVAFG---YLVFGQHEWNY----SNMIHATQTIFSYCVSAFQNTEFSGNKILGVLFLSSFM 2024

  Fly   570 FVVKYMLINL---IVSMMRDQMASVKADRDKKVRQRITF 605
            .|:..:.|||   ::....|:|.....:......:.:|:
  Rat  2025 LVMICIFINLFQVVILSAYDEMKQPVYEEPSDEAEAVTY 2063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brv1	NP_649116.1	PKD_channel	165..591	CDD:285288	90/494 (18%)
Pkdrej	NP_001128338.1	REJ	132..598	CDD:280229
		PLAT_polycystin	1111..1226	CDD:238850
		PKD_channel	1616..2046	CDD:285288	88/479 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276906at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10877
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920