Protein Alignment brv1 and pkd1l2

DIOPT Version :9

• Sequence 1: NP_649116.1
• Gene: brv1 / 40116
• FlyBaseID: FBgn0036874
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: XP_031756633.1
• Gene: pkd1l2 / 100486136
• XenbaseID: XB-GENE-968335
• Length: 2458
• Species: Xenopus tropicalis
• Alignment Length: 633
• Identity: 152/633 - (24%)
• Similarity: 262/633 - (41%)
• Gaps: 112/633 - (17%)

  Fly    34 YGKFNMI--LVAFLAVTLLQILIFT-PIKFTIMSLDAAFWPAHQAPETPDE-----NANVDTFMD 90
            |||.:.|  |:: :|::..:.|..| |:|  ::...|.|....:..|..||     |.|:.|..|
 Frog  1849 YGKDSSIKWLIS-MAISFFESLFITQPLK--VLGFAAFFALVLKKVEPEDEEETTINGNLSTPGD 1910

  Fly    91 NLRLRLRTLRSELM--------ITERHRNERVNLK-YRLITEELWLTGKLFLVYFFMALAFFDEL 146
            ...| |.:.|...:        ||:...|.....| :.||.|.|...|.|::: ..:|....|..
 Frog  1911 PNPL-LGSRRDSNIYQPPPPTDITKMKNNYMKEQKVFALIREILAYLGFLWML-LLVAYGQRDPN 1973

  Fly   147 LYFNTEATELLFQCNHGDAF-GLLSVGDVPDIYFFVVSSLVLAFTDGKNTSGGAPWIHAEG-TRL 209
            .|:..:..|..|.    |.| .|.|..:     ||..::..|.    .|..|..|....:| ::|
 Frog  1974 SYYLNKHIESSFT----DGFEDLCSYQE-----FFTWANTTLI----NNLYGSHPGFITDGNSKL 2025

  Fly   210 LGVVRLRQLRTESNRLGLSLPV-----FTERDFSESWTLPYERVPYTDKYW---------PIYTP 260
            :|..|:||:|.:.:    |.||     .|..:....::|..|.:.:.|..|         .:.:|
 Frog  2026 VGGARMRQIRIKKD----SCPVASVLQSTIDNCRAPYSLDAEEMGHYDGSWNFSAITNATDVNSP 2086

  Fly   261 WLPSVSVARDNLLMGINHVGHMFNYPESKGYKVLLSDTRHKSLKIIDYLMKKNWLDANTTALFMD 325
            |.    ....:.|.|....|.:..| ...||...|.:.|..:.:::..|....|||:.|.|:|::
 Frog  2087 WY----YQNHSKLRGHPTWGKLATY-RGGGYVADLGNERKYAHRVLQDLFSNIWLDSYTRAVFVE 2146

  Fly   326 FSLYNADANTFTVCTLWVE-----KFPYQYPDGHTR-----IESHTFVEQLREFTKFGMLMVFVF 380
            |::|||:.|.|.:..|..|     .|       .||     :..:.|.:.|..|.....::.|:|
 Frog  2147 FTVYNANVNLFCIVKLMFETNALGTF-------FTRANLQSVRLYPFTDGLHIFVVAAEVIYFLF 2204

  Fly   381 VVTWLQFT-KAFFLKVWYDPRQLKTLWVQVD-AMIV----ALSLVV-GMIMSVRDNLVQKMIKSV 438
            |:.::... |....:.|   ...::.|..:: |:|:    |||:.| ..|:..||....:..|:
 Frog  2205 VIYYMVVQGKRMKAEKW---GYFRSKWNLLELALIIISWSALSVYVKRTILGTRDLRYYQEHKN- 2265

  Fly   439 EIAVVVDFLDFRE----PAQLAYLEDVVTGLAVALVTMRLWKVLQFSATFQLFTKTIAMAWDALL 499
                  :|:.|.|    .|.|.||    ....|.|.|::||.:|:.:....:.|.|:..||..:.
 Frog  2266 ------EFVSFNETAAADAALGYL----IAFLVLLSTIKLWHLLRLNPKLNMITATLRRAWGDIS 2320

  Fly   500 CTFVITVIFIIAIGIATVTING----NYTSNFRDFPKGIVTVTCFAFGYTNLV-YPPDIFYGGEW 559
            ....:.||..:|..||...|.|    :|.:.| |..|.:|::....|.|..:: |.|.:   |.:
 Frog  2321 GFITVIVIMFLAYSIACNLIFGWKLNSYKTVF-DSAKTMVSLQLGIFNYEEVLDYNPVL---GSF 2381

  Fly   560 LGILLYTIMGFVVKYMLINLIVSMMRDQMASVKADRDKKVRQRITFWQ 607
            |.......|.|||..:.|::|:....::....:|..::::.: :..|:
 Frog  2382 LVGSCIIFMTFVVLNLFISVILVAFSEEQKHHQASDEEEIVE-LLLWK 2428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brv1	NP_649116.1	PKD_channel	165..591	CDD:285288	112/467 (24%)
pkd1l2	XP_031756633.1	CLECT	22..147	CDD:214480
		Gal_Lectin	163..243	CDD:396628
		REJ	<615..890	CDD:366875
		GPS	1276..1314	CDD:396408
		PLAT_polycystin	1385..1504	CDD:238850
		PKD_channel	1988..2408	CDD:400395	112/462 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276906at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10877
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020