Protein Alignment Chd3 and ATRX

DIOPT Version :10

• Sequence 1: NP_649111.1
• Gene: Chd3 / 40111
• FlyBaseID: FBgn0023395
• Length: 892
• Species: Drosophila melanogaster
• Sequence 2: NP_001184937.1
• Gene: ATRX / 837382
• AraportID: AT1G08600
• Length: 1479
• Species: Arabidopsis thaliana
• Alignment Length: 995
• Identity: 236/995 - (23%)
• Similarity: 379/995 - (38%)
• Gaps: 295/995 - (29%)

  Fly    35 EEYCKVCSDGGDLLCCDSCPSVYHRTCL-----SPPLKSIPKGDWICPRCIPLPGKAEKILSWRW 94
            |.:|:.|....||:.|.:|..::..:|:     ...:.......|.|..|.|:|
plant   524 ERHCEWCGHIADLIDCRTCEKLFCASCIKRNIGEEYMSEAQSSGWDCCCCSPIP----------- 577

  Fly    95 ALDR-SVELRTSKGEKRREYFIKWHGMSYWHCEWIPEGQMLLHHASMVASFQRRSDMEEPSLEEL 158
             |.| ::||..:..:|:                                |.:..||....|..:.
plant   578 -LQRLTLELEKAMRDKK--------------------------------SIELSSDSSSDSSSDN 609

  Fly   159 DDQDGNLHERFYRYGIKPEWLLVQRVINHSE--EPNGGTMYLVKWRELSYNDSSWERESDSIPGL 221
            :..|.:..........|.....::|:|:.:|  :.....:.:.|.|:            :.:..|
plant   610 NSVDTDADVNVTISSKKKSKKKIRRIIDDAELGKDTRTKIAIEKARQ------------ERLRSL 662

  Fly   222 NQAIALYKKLRSSNKGRQRDRPAPTIDLNKKYEDQPV-FLKEAG-------------LKLHPFQI 272
             |..|.||.:.|....:.....|....|...:....| .::|.|             ||:|  |:
plant   663 -QFSARYKTISSMGDVKSIPEGAEVEVLGDAHSGYIVNVVREIGEEAVRVPRSISAKLKVH--QV 724

  Fly   273 EGVSWLRYSW-------------GQGIPTILADEMGLGKTIQTVVFLYSLFKEGHC----RGPFL 320
            .|:   |:.|             .:|:..|||..||||||.|.:.|||:..:   |    ....|
plant   725 TGI---RFMWENIIQSISRVKSGDKGLGCILAHTMGLGKTFQVIAFLYTAMR---CVDLGLKTAL 783

  Fly   321 ISVPLSTLTNWERELELWAPELYCVTYVGGKTARAVIRKHEISFE---EVTTKTMRENQTQYKFN 382
            |..|::.|.||..|.|.|.|...       |..| :....::|.|   ::.||..::...   |.
plant   784 IVTPVNVLHNWRSEFEKWMPSEV-------KPLR-IFMLGDVSRERRFDLLTKWRKKGGV---FL 837

  Fly   383 VMLTSYEFISVDAAFLGCIDWAA--------------LVVDEAHRLRSNQSKFFRILSKYRIGYK 433
            :..|::..:|:..   |..|..|              ||.||||.:::.::...:.|.:.:...:
plant   838 MGYTNFRNLSLGR---GVKDLNAARGICNALRDGPDILVCDEAHIIKNTKADTTQALKQVKCQRR 899

  Fly   434 LLLTGTPLQNNLEELFHLLNFLSSGKFNDLQTFQAEFTDV--------SKEEQVK----RLHEIL 486
            :.|||:||||||.|.:.:::|:..|.......|:..|.:.        |..|.||    |.|.:.
plant   900 IALTGSPLQNNLMEYYCMVDFVREGFLGSSPEFRNRFQNPIENGQHMNSTAEDVKIMNQRSHILY 964

  Fly   487 E--PHMLRRLKADVL-KSMPPKSEFIVRVELSSMQKKFYKHIL--------------TKNFKA-- 532
            |  ...::|:..:|: |.:|||:.|::.|:||.:|:..|:..|              .|||.|
plant   965 EQLKGFVQRMDMNVVKKDLPPKTVFVISVKLSPLQRILYQRFLELYGFSDGRTDERMRKNFFAAY 1029

  Fly   533 ------LNQKG----------GGRVCSLLNIMMDLRKCCNHPYLFPSAAEEATIS---------- 571
                  ||..|          .||..|:::|..|.....|..|...:..::.|::
plant  1030 QVLAQILNHPGIPQLRSEDSKNGRRGSIVDIPDDCSSDENIDYNMVTGEKQRTMNDLQDKVDGYL 1094

  Fly   572 ---------PSGLYEMSSLTKASGKLDLLSKMLKQLKADNHRVLLFSQMTKMLNVLEHFL----- 622
                     ....|::|..   |||:.||..:|........:.|:|||....|:::|.:|
plant  1095 QKDWWVDLLQKNNYKVSDF---SGKMILLLDILSMSADVGDKALVFSQSIPTLDLIELYLSRVPR 1156

  Fly   623 ---EG----EGYQYDRIDGSIKGDLRQKAIDRFNDPVSEHF-VFLLSTRAGGLGINLATADTVII 679
               :|    :|..:.||||..:...|||.:||||:|.::.. ..|:|||||.|||||..|:.|||
plant  1157 HGKQGKFWKKGKDWYRIDGKTESSERQKLVDRFNEPDNKRVKCTLISTRAGSLGINLYAANRVII 1221

  Fly   680 FDSDWNPHNDVQAFSRAHRMGQKKKVMIYRFVTHNSVEERIMQVAKHKMMLTHLVVRPGMGGMTT 744
            .|..|||..|:||..||.|.||||.|..||.:...::||:|     :|..:|    :.|:.....
plant  1222 VDGSWNPTYDLQAIFRAWRYGQKKPVFAYRLMARGTIEEKI-----YKRQVT----KEGLAARVV 1277

  Fly   745 N-------FSKDELEDILRFGTEDLFKDGKSEAI----------HYD------------------ 774
            :       .||:|:..:..|..:    |.||||:          |.:
plant  1278 DRQQVHRTISKEEMLHLFEFDDD----DEKSEAVTEISKQNEAGHSNLVEQAILWTKKATLSRVG 1338

  Fly   775 -DKAVADLLDRTNRGIEEKESWANEYLSSFKVASYATKEDHEEH----------DDYNNDAENTD 828
             ||.:.:||.|      ...:|    :|||.......:|:.||.          :.|....|
plant  1339 GDKLMENLLQR------HGPNW----ISSFHEHETLLQENEEERLTKEEKDMAWEVYRRALE--- 1390

  Fly   829 PFYWENLMG---KSQPKLPK 845
               ||.:..   ...|.:||
plant  1391 ---WEEVQRVPFSESPVVPK 1407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chd3	NP_649111.1	PHD2_CHD_II	37..79	CDD:277007	9/46 (20%)
		CD_CSD	82..146	CDD:475127	7/64 (11%)
		CD2_tandem_CHD3-4_like	176..230	CDD:349309	9/55 (16%)
		PLN03142	266..>768	CDD:215601	171/621 (28%)
ATRX	NP_001184937.1	PRK02224	<1..>195	CDD:179385
		ADDz_ATRX	481..575	CDD:277252	11/50 (22%)
		HepA	<701..1278	CDD:440319	169/610 (28%)
		DEXHc_ARIP4	719..959	CDD:350827	69/261 (26%)