Protein Alignment Chd3 and PKR2

DIOPT Version :10

• Sequence 1: NP_649111.1
• Gene: Chd3 / 40111
• FlyBaseID: FBgn0023395
• Length: 892
• Species: Drosophila melanogaster
• Sequence 2: NP_194918.2
• Gene: PKR2 / 829320
• AraportID: AT4G31900
• Length: 1202
• Species: Arabidopsis thaliana
• Alignment Length: 872
• Identity: 347/872 - (39%)
• Similarity: 489/872 - (56%)
• Gaps: 138/872 - (15%)

  Fly    70 PKGDWI----------------------CPRCIPLPGKAEKILSWRWALDRSVELRTSKGEKR-- 110
            ||.|:|                      ||.     |:.||||...|....|....:|.....
plant    14 PKPDYIEDKLDEYIREEQVEETGGSNQDCPL-----GEIEKILDREWRPTASNNPNSSDNGTPTL 73

  Fly   111 ---REYFIKWHGMSYWHCEWIPEGQMLLHHAS--------MVASFQRRSDMEEPSLEELDDQDGN 164
               ::|.:||.|:||.||.|:||.:....:.|        .|..|....|        :...:..
plant    74 VVVKQYLVKWKGLSYLHCSWVPEQEFEKAYKSHPHLKLKLRVTRFNAAMD--------VFIAENG 130

  Fly   165 LHERFYRYGIKPEWLLVQRVINHSEEPNGGTMYLVKWRELSYNDSSWERESDSIPGLNQAIALYK 229
            .||..   .|:|||..|.|:| ...|.:.|..||||::||||.:|.||.||| |......|..:|
plant   131 AHEFI---AIRPEWKTVDRII-ACREGDDGEEYLVKYKELSYRNSYWESESD-ISDFQNEIQRFK 190

  Fly   230 KLRSSNK-----GRQRDRPAPTIDLNKKYEDQPVFLKEAGLKLHPFQIEGVSWLRYSWGQGIPTI 289
            .:.||::     ..:|:|     :..|:::..|.||...   ||.:|:||:::|||||.:....|
plant   191 DINSSSRRDKYVENERNR-----EEFKQFDLTPEFLTGT---LHTYQLEGLNFLRYSWSKKTNVI 247

  Fly   290 LADEMGLGKTIQTVVFLYSLFKEGHCRGPFLISVPLSTLTNWERELELWAPELYCVTYVGGKTAR 354
            ||||||||||||::.||.|||:|.  ..|.|:..||||:.|||||...|||.:..|.|.|...||
plant   248 LADEMGLGKTIQSIAFLASLFEEN--LSPHLVVAPLSTIRNWEREFATWAPHMNVVMYTGDSEAR 310

  Fly   355 AVIRKHEISFEEVTTKTMRENQTQYKFNVMLTSYEFISVDAAFLGCIDWAALVVDEAHRLRSNQS 419
            .||.:||..|.|         ..:.||:|:||:||.:....:.|..|.|..:::||.|||::.:|
plant   311 DVIWEHEFYFSE---------GRKSKFDVLLTTYEMVHPGISVLSPIKWTCMIIDEGHRLKNQKS 366

  Fly   420 KFFRILSKYRIGYKLLLTGTPLQNNLEELFHLLNFLSSGKFNDLQTFQAEFTDVSKEEQVKRLHE 484
            |.:..||::...:.:|||||||||||.|||.|::||.:.||..|:.||    |::||||:.|||:
plant   367 KLYSSLSQFTSKHIVLLTGTPLQNNLNELFALMHFLDADKFGSLEKFQ----DINKEEQISRLHQ 427

  Fly   485 ILEPHMLRRLKADVLK-SMPPKSEFIVRVELSSMQKKFYKHILTKNFKALNQKGGGRVCSLLNIM 548
            :|.||:|||||.|||| .:|||.|.|:||::||.||:.||.::|.|::.|.:|   |...:.|::
plant   428 MLAPHLLRRLKKDVLKDKVPPKKELILRVDMSSQQKEVYKAVITNNYQVLTKK---RDAKISNVL 489

  Fly   549 MDLRKCCNHPYLFP------SAAEEATISPSGLYEMSSLTKASGKLDLLSKMLKQLKADNHRVLL 607
            |.||:.|:||||.|      ..|.||         .:.|.:|||||.||.||:.:||...||||:
plant   490 MKLRQVCSHPYLLPDFEPRFEDANEA---------FTKLLEASGKLQLLDKMMVKLKEQGHRVLI 545

  Fly   608 FSQMTKMLNVLEHFLEGEGYQYDRIDGSIKGDLRQKAIDRFNDPVSEHFVFLLSTRAGGLGINLA 672
            ::|....|.:||.:...:.:.|:||||.|.|..||..|||||...|..|.|||||||||:|||||
plant   546 YTQFQHTLYLLEDYFTFKNWNYERIDGKISGPERQVRIDRFNAENSNRFCFLLSTRAGGIGINLA 610

  Fly   673 TADTVIIFDSDWNPHNDVQAFSRAHRMGQKKKVMIYRFVTHNSVEERIMQVAKHKMMLTHLVVRP 737
            |||||||:|||||||.|:||.:|.||:||..||||||.:...:||||:|::.|:||:|.||||.
plant   611 TADTVIIYDSDWNPHADLQAMARVHRLGQTNKVMIYRLIHKGTVEERMMEITKNKMLLEHLVVG- 674

  Fly   738 GMGGMTTNFSKDELEDILRFGTEDLFKD-----GKSEAIHYDDKAVADLLDRTN-----RGIEEK 792
                 ..:..:|||:||:::|:::||.:     |:|..|||||.|:..||||.:     ..::::
plant   675 -----KQHLCQDELDDIIKYGSKELFSEENDEAGRSGKIHYDDAAIEQLLDRNHVDAVEVSLDDE 734

  Fly   793 ESWANEYLSSFKVASYATKEDHEEHD--------DYNNDAENTD-PFYWENLMGKSQPKLPKKQK 848
            |.  .::|.:|||||:...:|..|..        :.|:...|.| ..:|::|:         |.|
plant   735 EE--TDFLKNFKVASFEYVDDENEAAALEEAQAIENNSSVRNADRTSHWKDLL---------KDK 788

  Fly   849 KQSQQSQVDVESIMGKGKRIRKEIDYS 875
            .:.||:  :..|.:||.||..|::.|:
plant   789 YEVQQA--EELSALGKRKRNGKQVMYA 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chd3	NP_649111.1	PHD2_CHD_II	37..79	CDD:277007	6/30 (20%)
		CD_CSD	82..146	CDD:475127	22/76 (29%)
		CD2_tandem_CHD3-4_like	176..230	CDD:349309	24/53 (45%)
		PLN03142	266..>768	CDD:215601	246/513 (48%)
PKR2	NP_194918.2	CD1_tandem	43..118	CDD:349307	22/79 (28%)
		CD2_tandem	140..191	CDD:349306	23/52 (44%)
		HepA	<202..674	CDD:440319	242/506 (48%)
		DUF1087	<774..816	CDD:461922	15/51 (29%)
		CHDII_SANT-like	856..999	CDD:461920