Protein Alignment Chd3 and lds

DIOPT Version :10

• Sequence 1: NP_649111.1
• Gene: Chd3 / 40111
• FlyBaseID: FBgn0023395
• Length: 892
• Species: Drosophila melanogaster
• Sequence 2: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Alignment Length: 781
• Identity: 183/781 - (23%)
• Similarity: 320/781 - (40%)
• Gaps: 214/781 - (27%)

  Fly   141 VASFQRRSDMEEPSLEELDDQDGNLHERFYRYGIKPEWLLVQRVINHSEEPNGGTMYLVKWRELS 205
            :.:.:|...|:|..:..|..|..|:          |...:|:..:|....|:..|:   .|.|||
  Fly   331 IDTLRRELAMDEQWISALRVQQSNV----------PAVRVVKPTLNPPRAPSIDTL---DWDELS 382

  Fly   206 YNDSSWERESDSIPGL----NQAIALYKKLRSSNKGRQRDRPAPTIDLNKKYEDQPVFLKEAGLK 266
            ...:..:.......|:    ||.....:.|:..:...: |.|.|.:     ..:.||.||   :.
  Fly   383 EAVNEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLE-DLPGPEV-----LAEDPVGLK---VS 438

  Fly   267 LHPFQIEGVSWLRYSWGQ-GIPT--ILADEMGLGKTIQTVVFLYSLFKEGH-------------- 314
            |...|...::|:  ||.: .:|.  ||||:||||||: |::......|.|.
  Fly   439 LMNHQKHALAWM--SWRERKLPRGGILADDMGLGKTL-TMISSVLACKNGQEMSEGKDESSDSDS 500

  Fly   315 ----------------------CRGPFLISVPLSTLTNWERELELWAPELYCVTYVGGKTAR--A 355
                                  .||..|:..|.|.|..||.|:|             .|.:|  .
  Fly   501 EDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVE-------------SKVSRQKL 552

  Fly   356 VIRKHEISFEEVTTKTMRENQTQYKFNVMLTSYEFI-----SVDAAFLGCIDWAALVVDEAHRLR 415
            .:..|..:..|...|.:|:      :::::|:|:.:     |:.|.|  .:.|..:::||||.:|
  Fly   553 TVCVHHGNNRETKGKYLRD------YDIVVTTYQIVAREHKSLSAVF--GVKWRRIILDEAHVVR 609

  Fly   416 SNQSKFFRILSKYRIGYKLLLTGTPLQNNLEELFHLLNFLSSGKFNDLQTFQAEFTDVSKEEQVK 480
            :::|:....:...|..|:..|||||:||...:::.||.||....|:||.|::....:.|...| .
  Fly   610 NHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAGGQ-N 673

  Fly   481 RLHEILEPHMLRRLKADV-----LKSMPPKSEFIVRVELSSMQKKFYKHILT------------- 527
            ||:.:::..||||.||.:     |.|:|.|...::.:.|...:...|:.::|
  Fly   674 RLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQR 738

  Fly   528 ------------KNFKALNQ---------------------KGGGRVCSLLNIMMDLRKCCNHPY 559
                        .|....||                     |...:...:|.:::.||:.|.||.
  Fly   739 AERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPG 803

  Fly   560 LF------------------------------------------------------PSAAEEATI 570
            |.                                                      |...:||.|
  Fly   804 LIDAMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARI 868

  Fly   571 SPS--GLYEMS----SLTKASGKLDLLSKMLKQ--LKADNHRVLLFSQMTKMLNVLEHFLEGEGY 627
            :.:  .|.:.|    :|.:.|.|::::.::||.  ||:.:.:.::.||.|.:|::|...|..:|.
  Fly   869 AKASKNLLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGV 933

  Fly   628 QYDRIDGSIKGDLRQKAIDRFNDPVSEHFVFLLSTRAGGLGINLATADTVIIFDSDWNPHNDVQA 692
            ....::|:|....||..::.|||..::..|.|||..|||:|:||..|:.:::.|..|||..:.||
  Fly   934 ATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQA 998

  Fly   693 FSRAHRMGQKKKVMIYRFVTHNSVEERIMQVAKHKMMLTHLVVRPGMGGMTTNFSKDELEDILRF 757
            ..|.:|:||||.|:||:|:..::||:||..:...|:.|...|:....  :::..:.|:|:.:  |
  Fly   999 QDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGAK--VSSKLTIDDLKGL--F 1059

  Fly   758 G 758
            |
  Fly  1060 G 1060

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chd3	NP_649111.1	PHD2_CHD_II	37..79	CDD:277007
		CD_CSD	82..146	CDD:475127	0/4 (0%)
		CD2_tandem_CHD3-4_like	176..230	CDD:349309	12/57 (21%)
		PLN03142	266..>768	CDD:215601	157/652 (24%)
lds	NP_524850.2	HepA	287..1041	CDD:440319	178/756 (24%)
		DEXHc_TTF2	439..686	CDD:350830	70/271 (26%)