Protein Alignment Chd3 and rrp1

DIOPT Version :10

• Sequence 1: NP_649111.1
• Gene: Chd3 / 40111
• FlyBaseID: FBgn0023395
• Length: 892
• Species: Drosophila melanogaster
• Sequence 2: NP_594246.1
• Gene: rrp1 / 2542440
• PomBaseID: SPAC17A2.12
• Length: 897
• Species: Schizosaccharomyces pombe
• Alignment Length: 701
• Identity: 167/701 - (23%)
• Similarity: 280/701 - (39%)
• Gaps: 209/701 - (29%)

  Fly   239 QRDRPAP--TIDLNKKYEDQPVFLKEAGL--KLHPFQIEGVSWLRYSWGQGIPT--ILADEMGLG 297
            |.:.|:|  ||||..|.|.    ::.|||  .|.|.|:||.:|:. |..|....  ::||:||||
pombe   222 QHNTPSPFDTIDLQLKNEQ----VQSAGLLVSLLPHQVEGHAWME-SMEQSSKCGGVMADDMGLG 281

  Fly   298 KTIQTVVFLYSLFKEGHCRGPFLISVPLSTLTNWERELELWA-PELYCVTYVGGKTARAVIRKHE 361
            |||||:..|.:...:...|...||.|.::.|..|..||.... |......|:...:.:..:..:|
pombe   282 KTIQTIALLLTQKSQDPLRKTNLIVVSVALLHQWAEELSTKVHPSKKLSVYIHHGSTKKNLDSYE 346

  Fly   362 ISFEEVTTKTMRENQTQYKFNVMLTSYEFISVD-------------------AAFLGCIDWAALV 407
            :|                :::|:||:|..::.:                   |..|....|..:|
pombe   347 LS----------------QYDVVLTTYSMLAYEMKQNDAFNNNNPATATPPPACSLLETSWYRIV 395

  Fly   408 VDEAHRLRSNQSKFFRILSKYRIGYKLLLTGTPLQNNLEELFHLLNFLSSGKF-----------N 461
            :||||.:|:..:...:...|....|:..|:|||:||:::|.:.||.||....:           .
pombe   396 LDEAHTIRNRDTLAAKCCVKLDAKYRWCLSGTPIQNHIDEFYSLLKFLRIKPYCVWSLFAKDISR 460

  Fly   462 DLQTFQAEFTDVSKEEQVKRLHEILEPHMLRRLKAD-----VLKSMPPKSEFIVRVELSSMQKKF 521
            .|::::|:..    |..:|||..:|...:.||.|..     .:.::|||:...|.|.|...::..
pombe   461 PLKSYRADIV----EAALKRLRILLASTVFRRTKETRVNNLPIVNLPPKTIRTVSVNLLPEERAL 521

  Fly   522 YKHILTKNFKAL-----NQKGGGRVCSLLNIMMDLRKCCNHPYLFPSAAEE-------------- 567
            |...::.....:     |.....|...||..::.||:.|.||:|..|::.:
pombe   522 YNEQMSSAQSLVDNYFNNDHDLSRYGFLLVSLLRLRQFCCHPWLVKSSSLDNSFRIRDSENVRNA 586

  Fly   568 ------------AT------------------ISPSGLYE----MSSLT----KASGKLDLLSK- 593
                        ||                  |.|.|.:.    ||.|.    .:|....:::|
pombe   587 CKSLDPLTIERIATLQDFNCSVCLDPCLAPVFIIPCGHFTCQECMSMLVGQKYGSSSTSTIIAKC 651

  Fly   594 --------------------------MLKQLKAD------------------------------- 601
                                      .||||:.|
pombe   652 PMCRGNIVQDSLVDATILQAIHGPLNSLKQLELDMNQSFSEQESIKLRWENRIDQMFTKKFGKRA 716

  Fly   602 ------------------------NHRVLLFSQMTKMLNVLEHFLEGEGYQYDRIDGSIKGDLRQ 642
                                    |.::|::||.::.|.::.|.|:.|..::.|.||::..:.||
pombe   717 SEWKSSSKLNQARQTILDIIGSKRNEKILVYSQFSQYLCLVSHMLKLENIRHVRYDGTMSANQRQ 781

  Fly   643 KAIDRFNDPVSEHFVFLLSTRAGGLGINLATADTVIIFDSDWNPHNDVQAFSRAHRMGQKKKVMI 707
            |::..||:. .:..|.|:|.:||.:|:||..|:.||:.:..:||..:.||..|.||:||:|.|.:
pombe   782 KSLHSFNND-KDVLVMLVSLKAGSVGLNLTIANHVILQEPFYNPSIEDQAIDRVHRLGQQKPVTV 845

  Fly   708 YRFVTHNSVEERIMQVAKHKMMLTHLVVRPGMGGMTTNFSKDELEDILRFG 758
            |||:|.:::||||:.|.:.|..|....:........:...|:||  :..||
pombe   846 YRFITKDTIEERIVSVQRKKRQLVKEALDSNENNPLSRLDKEEL--LYLFG 894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chd3	NP_649111.1	PHD2_CHD_II	37..79	CDD:277007
		CD_CSD	82..146	CDD:475127
		CD2_tandem_CHD3-4_like	176..230	CDD:349309
		PLN03142	266..>768	CDD:215601	155/670 (23%)
rrp1	NP_594246.1	HepA	<244..874	CDD:440319	153/651 (24%)
		RING_Ubox	603..663	CDD:473075	8/59 (14%)