DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chd3 and phf-32

DIOPT Version :9

Sequence 1:	NP_649111.1	Gene:	Chd3 / 40111	FlyBaseID:	FBgn0023395	Length:	892	Species:	Drosophila melanogaster
Sequence 2:	NP_001355360.1	Gene:	phf-32 / 184600	WormBaseID:	WBGene00008902	Length:	208	Species:	Caenorhabditis elegans

Alignment Length:	223	Identity:	56/223 - (25%)
Similarity:	89/223 - (39%)	Gaps:	55/223 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DPDWKTPGKASKDKRPKTNAKKQKFRDEEYCKVCSDGGDLLCCDSCPSVYHRTCLSPPLKSIP-- 70
            ||  |..|:.|.....:.:.:...:.::..|.:|:|||.::.|::||:.:|..||.  ||:||
Worm     4 DP--KMRGECSSSATSEPDDQNWLWPEQNKCGMCADGGTIIWCETCPASFHAFCLG--LKTIPEP 64

  Fly    71 -KGDWICPR---------CIPLPGKAEKILSWRWALDRSVELRTSKGEKRREYFIKWHGMSYWHC 125
             |..:||.|         .:|..||         ...::|.|:|.             ||.....
Worm    65 EKDTFICHRDKISKNNRLAVPSEGK---------VFIQNVFLQTM-------------GMLNPMN 107

  Fly   126 EWIPEGQMLLHHASMVASFQRRSDMEEPSLEELDDQDGNLHERFYRYGIK-PEWLLVQRVINHSE 189
            ..|||.: ..|....||:...::..:..||:....|..:|.||.....|| .|.:|..|.|..:|
Worm   108 TKIPEIE-AFHETINVANTDIQTSTKNTSLDGKIKQYSDLEERNLDIFIKCCESMLELRKILEAE 171

  Fly   190 E----PNGG-----------TMYLVKWR 202
            .    |..|           |:.::|.|
Worm   172 NLDLLPRAGKCGTKRTTVAATLKIIKLR 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chd3	NP_649111.1	PHD2_CHD_II	37..79	CDD:277007	19/53 (36%)
		CHROMO	85..147	CDD:237991	12/61 (20%)
		CHROMO	181..233	CDD:214605	8/37 (22%)
		SNF2_N	270..561	CDD:278600
		DEXDc	288..440	CDD:238005
		Helicase_C	585..700	CDD:278689
phf-32	NP_001355360.1	PHD_SF	32..71	CDD:389947	16/40 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0383
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810