Protein Alignment Chd3 and LOC1273471

DIOPT Version :10

• Sequence 1: NP_649111.1
• Gene: Chd3 / 40111
• FlyBaseID: FBgn0023395
• Length: 892
• Species: Drosophila melanogaster
• Sequence 2: XP_312449.5
• Gene: LOC1273471 / 1273471
• VectorBaseID: AGAMI1_011781
• Length: 1503
• Species: Anopheles gambiae
• Alignment Length: 863
• Identity: 192/863 - (22%)
• Similarity: 339/863 - (39%)
• Gaps: 263/863 - (30%)

  Fly   186 NHSEEPNGGTMYLVK------WRELSYNDSSWERESDSIPGLNQAIALYKKLRS---SNKGRQ-- 239
            :..:.||.|...:.|      ..|.:.|....|||.      .|.||..:||.:   ..|..:
Mosquito   501 SEGDSPNKGRKNIRKLLKKSDLEETTKNAEQEERER------KQRIAERQKLYNQVYDEKPEEAC 559

  Fly   240 ----------RDRPAPTIDLNKKYEDQPVFLKEAGLKLHPFQIEGVSWL---------RYSWGQG 285
                      .:...|.:::::|...|          |.|.|..|:.::         :.:..:|
Mosquito   560 TLDQLVLDFDEETKEPLLEVDRKLVKQ----------LKPHQANGIKFMFDACFESLEQMNQSKG 614

  Fly   286 IPTILADEMGLGKTIQTVVFLYSLFKEGHCRG--PFLISVPLSTLTNWERELELWAPELYCVTYV 348
            ...|||..||||||:|.|...::|.......|  ..|:..||||:.||..|..:|...:...|.|
Mosquito   615 SGCILAHCMGLGKTLQVVTLAHTLLASADLTGVERILVVCPLSTVLNWANEFHMWMKHVKKGTEV 679

  Fly   349 GGKTARAVIRKHEIS-FEEVTTKTMRENQTQYKFNVMLTSYEFI-----------------SVDA 395
                     ..:||| :::..|:..:..:...:..||:..|:..                 |:..
Mosquito   680 ---------EVYEISKYKDNVTRANKLMEWHNEGGVMIMGYDMFRNLANPTATRIRKKVRESLQT 735

  Fly   396 AFLGCIDWA--ALVVDEAHRLRSNQSKFFRILSKYRIGYKLLLTGTPLQNNLEELFHLLNF---- 454
            :.   ||..  .:|.||.|.|::.::...:.:::.....:::|||||:|||::|.:.::.|
Mosquito   736 SL---IDPGPELIVCDEGHLLKNEKTSLSQAVNRISTMRRIVLTGTPIQNNMKEYYCMVQFVKPK 797

  Fly   455 ---------------LSSGKFNDLQTFQAEFTDVSKEEQVKRLHEILEPHMLRRLKADVLKSMPP 504
                           :::|::.|...:..:.  :.|...|  ||::|:..:.||..|.:...:||
Mosquito   798 LLGTYTEYMNRFVNPITNGQYTDSTPYDIQL--MRKRAHV--LHKLLDGCVQRRDYAVLAPFLPP 858

  Fly   505 KSEFIVRVELSSMQKKFYKHILTKNFKALNQKGG--------GRVCSLLNIMMDLRKCCNHPYLF 561
            |.||:|.::|:.:|...||:.:.      |..|.        .|...|.|...:|::...||.:.
Mosquito   859 KLEFVVSIKLTPLQSTLYKYYME------NMAGKRNDDDPTLKRSSMLFNDFQNLQRIWTHPRVL 917

  Fly   562 ----------------------------------------PSAAE-------------------- 566
                                                    |::::
Mosquito   918 RYNSDRYEIKQQRKRDLDSENESEGSMKDFIDDEDTAESTPASSDSESDVQSVHDDSSRDAKSSG 982

  Fly   567 -------EATI-------------------------SPSGLY-------EMSSLTKASGKLDLLS 592
                   :||:                         :|:..:       |:.:| :.||||.:|.
Mosquito   983 DSTSNKRKATVGTRSTRNNPNFNGGDDDDVIMQKPENPTEWWMQMCPETELDNL-EHSGKLVVLM 1046

  Fly   593 KMLKQLKADNHRVLLFSQMTKMLNVLEHFL----------EGE--------------GYQYDRID 633
            ::||:.:|...::|:|||....|:|:||||          |.|              |..|.|:|
Mosquito  1047 EILKECEAIGDKLLVFSQSLYSLDVIEHFLSLLDENLQKDEDERDEQLSKYPGSWSLGLDYFRLD 1111

  Fly   634 GSIKGDLRQKAIDRFNDPVSEHF-VFLLSTRAGGLGINLATADTVIIFDSDWNPHNDVQAFSRAH 697
            ||...|.|..|...|||..:... :||:|||||||||||..|:.|:|||..|||.:|:|:..|.:
Mosquito  1112 GSTSIDNRNDACKVFNDESNTRARLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDIQSIFRVY 1176

  Fly   698 RMGQKKKVMIYRFVTHNSVEERIMQVAKHKMMLTHLVVRPGMGGMTTNFSKDELEDILRFGTEDL 762
            |.||.|...||||:...::||:|.:....|..::..|:....  :..::.:::|:::.|:..|.
Mosquito  1177 RFGQSKPCYIYRFIAMGTMEEKIYERQVTKQAISKRVIDEQQ--IDRHYKENDLQELYRYEVET- 1238

  Fly   763 FKDGKSEAIHYDDKAVADLLDRTNRGIEEKESWANEYLSSFKVASYATKEDHEEHDDYNNDAENT 827
             .:.:.......|:..|:||.|.:..|             :|...:.:..:::|.:..|.:....
Mosquito  1239 -SEPRPTPNVPKDRLFAELLKRFDPLI-------------YKYHEHDSLLENKEEETLNEEERKA 1289

  Fly   828 DPFYWENL-MGKSQPKLP 844
               .||.. ..|::|.:|
Mosquito  1290 ---AWEEFEQEKNRPPMP 1304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chd3	NP_649111.1	PHD2_CHD_II	37..79	CDD:277007
		CD_CSD	82..146	CDD:475127
		CD2_tandem_CHD3-4_like	176..230	CDD:349309	12/49 (24%)
		PLN03142	266..>768	CDD:215601	160/683 (23%)
LOC1273471	XP_312449.5	None