Protein Alignment Chd3 and LOC1271255

DIOPT Version :10

• Sequence 1: NP_649111.1
• Gene: Chd3 / 40111
• FlyBaseID: FBgn0023395
• Length: 892
• Species: Drosophila melanogaster
• Sequence 2: XP_061510596.1
• Gene: LOC1271255 / 1271255
• VectorBaseID: AGAMI1_006303
• Length: 3078
• Species: Anopheles gambiae
• Alignment Length: 1019
• Identity: 239/1019 - (23%)
• Similarity: 382/1019 - (37%)
• Gaps: 319/1019 - (31%)

  Fly     7 ADPDWKTPGKASKDKRPKTNAKKQKFRDEEYCKVCSDGGDLLCCDSCPSVYHRTCLSP------- 64
            :|...|||.|    :|.:.||:|.:..:.|.....:| .||...|..|....|...:|
Mosquito   907 SDKSEKTPRK----RRKRINARKARGSESERESSSAD-SDLEMLDGTPKKRQRKRAAPVSLETFD 966

  Fly    65 ----------PLKS--------------------IPKGDWI----CPRCIPLPGKAEKILSWRWA 95
                      |.||                    .|.||.|    .....|.|...:...:...|
Mosquito   967 FSASLNASAAPRKSKTPASTACEGSTIAKPSPSTTPSGDGIKGKQAKTSSPAPSDPDATTTGSGA 1031

  Fly    96 LDRSVELRTSKGEKRREYFIKWHGMSYWHCEWIPEGQMLLHHASMVASFQRRSDMEEPSLEELDD 160
            ...:....::.|:::..                .:||                |....|.:..||
Mosquito  1032 AATAASGSSTAGKQKGS----------------KDGQ----------------DCISLSSDSSDD 1064

  Fly   161 QD---GNLHERFYRYGIKPEWLLVQRVINHSEEPNGGTMYLVKWRELSYNDSSWERESDSIPGLN 222
            .:   |:|.|.    ...|:           :||..      :.|.:..||
Mosquito  1065 AELITGDLEEN----KTVPD-----------KEPKR------RIRAMLTND-------------- 1094

  Fly   223 QAIALYKKLRSSNKGRQRDRPAPTIDLNKKYEDQPVFL-------------------KEAGLKLH 268
                   :|....|..|::....|..|.||:|....||                   ::..:.:|
Mosquito  1095 -------ELAEETKKAQKEEEGRTARLKKKHEQLKKFLASYLPGPGESELVLDYDSVRKQAICVH 1152

  Fly   269 --------PFQIEGVSWL---RYSWGQGIP------TILADEMGLGKTIQTVVFLYSLFKEGHCR 316
                    |.||||:.::   .|.....:|      .|||..||||||:|.:..|:::.     |
Mosquito  1153 PEIVKLLKPHQIEGIKFMYDNTYGSVDALPKHSGSGCILAHCMGLGKTLQMISLLHTVM-----R 1212

  Fly   317 GP------FLISVPLSTLTNWERELELW--------APELYCVTYVGGKTARAVIRKHEISFEEV 367
            .|      .|:..|.||:.||:.|:..|        ..::||...|..:..:..:.|.....:..
Mosquito  1213 YPQLMTNRVLVICPKSTVMNWKEEIARWQGTIRTGYQMKVYCFPDVCTQNDKIAVLKRWYYCKSP 1277

  Fly   368 TTKTMRENQTQYKFNVMLTSYE----FISVDAAFLGCI------DWAALVV-DEAHRLRSNQSKF 421
            ....|......::   .|.:||    .:.:.:|.||.|      ..|.||: ||.|::::.:|..
Mosquito  1278 NCGVMLIGYEAFR---ALINYERRKGSVGLRSAKLGLIKEYLLNPGADLVICDEGHQIKNKRSAI 1339

  Fly   422 FRILSKYRIGYKLLLTGTPLQNNLEELFHLLNFL------SSGKF-----NDLQTFQAEFTDVSK 475
            ...:||.:...:::|||||:||||:|.:.::||:      |..:|     |.::..|.:.:|...
Mosquito  1340 SEAVSKIKTRRRIMLTGTPIQNNLKEYYCMVNFIKPSFLGSDKEFSNLYANPIKNGQCKDSDHQS 1404

  Fly   476 EEQVKR----LHEILEPHMLRRLKADVLKS-MPPKSEFIVRVELSSMQKKFYKHILTKNFKALNQ 535
            .:.:|:    ||..|. ..::|.:|.|||. :|.|.|:::.|.|:.:|:|.|:..|..|....|.
Mosquito  1405 IKIMKQRSYVLHNKLS-KFVQRKEAAVLKEFLPEKFEYVLFVPLTPVQEKMYEVFLQMNDYTNND 1468

  Fly   536 KGG--GRV--CSLLNIMMDLRKCCNHPYLFPSAAEEATI-------------------SP----- 572
            ..|  ||.  ..|:.....|||...||.:...|.|.|.:                   ||
Mosquito  1469 VTGEPGRTKKFKLIADYTSLRKIWTHPKVLEKAWESANLEKNRRDAARKTATPDSDDESPDDHND 1533

  Fly   573 --SG--------------LYEMSSLTKASGKLDLLSKMLKQLKADNHRVLLFSQMTKMLNVLEHF 621
              ||              :.::.||. .|.||.:|.::||.......:||:|:....:||::|||
Mosquito  1534 IKSGQLSVTNDWWRQYLQIADLESLF-PSNKLWILFEILKHCNERGEKVLIFTAFVSVLNMVEHF 1597

  Fly   622 L---------------------EG---EGYQYDRIDGSIKGDLRQKAIDRFNDPVSEHF-VFLLS 661
            :                     :|   .|..|.|:||..:..:|.:.|..||||.::.. .||:|
Mosquito  1598 MAKIHHQEENPQLSDAYAYSAFKGPWEPGKDYYRLDGKTQKSIRHQMITSFNDPQNKRTKCFLIS 1662

  Fly   662 TRAGGLGINLATADTVIIFDSDWNPHNDVQAFSRAHRMGQKKKVMIYRFVTHNSVEERI------ 720
            .:|||.||||..|:.|||.|:.|||.||.|...|..|:|||:|..:||.:...::||::
Mosquito  1663 AKAGGQGINLTGANRVIILDTSWNPSNDQQNIFRIFRLGQKRKCYVYRLIAAGTMEEKVYSRSVT 1727

  Fly   721 -----------MQVAKHKMM--LTHLVVRPGMGGMTTNF----SKDELEDILRFGTEDLFKDGKS 768
                       .|:.:|...  |..|.....:..||...    :.|.|..:||.....:.|..:.
Mosquito  1728 KQALSFRVVDEQQIDRHYSYGELAELYTLTKVSEMTRETPILPADDILASLLRTYPNKILKYHEH 1792

  Fly   769 EAIHYDDKAVADLLDRTNRGIEEKESWA--------NE---YLS 801
            ::: .::|...||.:.     |:||:||        ||   |||
Mosquito  1793 DSL-LENKPEQDLSEE-----EKKEAWAAYEREIQNNENRSYLS 1830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chd3	NP_649111.1	PHD2_CHD_II	37..79	CDD:277007	14/82 (17%)
		CD_CSD	82..146	CDD:475127	5/63 (8%)
		CD2_tandem_CHD3-4_like	176..230	CDD:349309	6/53 (11%)
		PLN03142	266..>768	CDD:215601	173/651 (27%)
LOC1271255	XP_061510596.1	None