DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pip and Hs2st1

DIOPT Version :9

Sequence 1:	NP_788536.1	Gene:	pip / 40104	FlyBaseID:	FBgn0003089	Length:	514	Species:	Drosophila melanogaster
Sequence 2:	XP_008759717.1	Gene:	Hs2st1 / 292155	RGDID:	1305366	Length:	357	Species:	Rattus norvegicus

Alignment Length:	381	Identity:	100/381 - (26%)
Similarity:	172/381 - (45%)	Gaps:	68/381 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 HQQEKIDGHKHKASHDKQLAVPDNKHKEDEVHYEDDEDEVEENDDDLANDVGTTDSEGFNFKADL 205
            :|.:|::  :.:|..::.:|    :|:..|:......|...::        .|.|.|     .|:
  Rat    29 NQIQKLE--ESRAKLERAIA----RHEVREIEQRHTMDGPRQD--------ATLDEE-----EDI 74

  Fly   206 LNNTKYAEVDFVFFNRVPKVGSQSLMELMARLGKINGFTHARNKGSAHETIVMNKQRQNDLIADL 270
            :          :.:|||||..|.|...:...|...|.: |..:..:.....||:.|.|...:.::
  Rat    75 V----------IIYNRVPKTASTSFTNIAYDLCAKNRY-HVLHINTTKNNPVMSLQDQVRFVKNI 128

  Fly   271 LT--RPKPHIYSQHIAYINFTRFHL-PKPIYINLIRDPIDRIISWHYYIRAPWYYRD--MQAKLG 330
            .:  ..||..|..||:|::|.:|.: .||||||::||||:|::|::|::|....||.  .:.|.|
  Rat   129 TSWNEMKPGFYHGHISYLDFAKFGVKKKPIYINVVRDPIERLVSYYYFLRFGDDYRPGLRRRKQG 193

  Fly   331 ENAIPMPSEEFMNLDLDTCVRNHDPHCTFTQMQIKNPVGDHRRQTLFFCGMNQKLCMPFNSEAAM 395
            :..           ..|.||......|...::.::.|         ||||.:.: |....|..||
  Rat   194 DKK-----------TFDECVAEGGSDCAPEKLWLQIP---------FFCGHSSE-CWNVGSRWAM 237

  Fly   396 QKAKRTVETEYAVVGTWEDTNITLSVLEAYIPRYFRNAKVAY-YLGKDRLSRVNRNNVTRIVSDE 459
            .:||..:..||.:||..|:....:.:|||.:||:||.|...| .:||.  |.:.:....::.:.:
  Rat   238 DQAKYNLVNEYFLVGVTEELEDFIMLLEAALPRFFRGATDLYRTVGKK--SHLRKTTEKKLPTKQ 300

  Fly   460 TRLILRKN--LTNEIEFYEFCKQRLYLQYAALSHGKRFGEDD-YLLVPEQQNEYNE 512
            |...|:::  ...|.|||||..::.....|   |..|..:.| |:|.   ||.:.|
  Rat   301 TIAKLQQSDIWKMENEFYEFALEQFQFMRA---HAVREKDGDLYILA---QNFFYE 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pip	NP_788536.1	Sulfotransfer_2	212..477	CDD:281554	78/272 (29%)
Hs2st1	XP_008759717.1	Sulfotransfer_2	71..327	CDD:281554	82/294 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3922
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375927at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820