Protein Alignment Gbs-76A and PIG2

DIOPT Version :10

• Sequence 1: NP_649104.1
• Gene: Gbs-76A / 40102
• FlyBaseID: FBgn0036862
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_012219.3
• Gene: PIG2 / 854766
• SGDID: S000001307
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 613
• Identity: 127/613 - (20%)
• Similarity: 214/613 - (34%)
• Gaps: 203/613 - (33%)

  Fly   124 LIETASNTPHNSTAESGYACASMASSHSSSNDGPYFDASASTSTAAAAQDQTLPASEHKEYVNTL 188
            |::...|.|:|             |:|:::    |.:.:|:..|.|.......||.     :|:|
Yeast    11 LMDEPLNLPNN-------------SAHNNN----YGNINANIRTFAGMSMHMHPAR-----LNSL 53

  Fly   189 Q-LNGKHGLANGVQEEQPAFQDDVQEDEAFLQAQILNELQKHSNSLTEVEQTKP--EEGKLTNGH 250
            : |:....|:|......|  ||::|.:....:....|..|.|::        .|  ..|...|.|
Yeast    54 EFLHKPRRLSNVKLHRLP--QDELQRNTDMNKGMYFNGKQVHAH--------HPFINSGANFNAH 108

  Fly   251 LEKVEEL-ELKDVLEVAGTTNRAPKVIAAPQEVEAFADRSQEQ-SPNDRVQK------ESSQERV 307
            .:.|.:| |.:|.:              :|...:.|...|:|. :|:..:.|      :||.:|.
Yeast   109 HQDVSKLGEEEDEI--------------SPLSHDNFQYESEENGNPSPPIYKKSGELVKSSLKRR 159

  Fly   308 PEGTP------FEGVQGESPS---DRVQT---------------------------DASDERVQE 336
            .:..|      |.....:|..   |.|.|                           |...:.||:
Yeast   160 SKSLPITPKSIFNKTGSKSKHVNLDHVDTRLLQRSKSVHFDRVLPIKLFNENEKPIDVGKQMVQQ 224

  Fly   337 EISNDTVQVESNHKSAT---------ESISTEVTTLERSPEESRNDELSPDSGV----------- 381
            ::.|      ..||..|         :|:..|....|.:..|..:..|....||
Yeast   225 DVLN------FKHKPLTRLSALNGGSDSVPIEDLLSENNQNEYGDTWLQNPKGVFLFGTNSNNRR 283

  Fly   382 ----------DETDKSASNLTVDVDLAQIEQAKQDATEAVEKSGAPSRGTTVDTTDDEDDCRPQR 436
                      |::|....|.:.|.....:.|  ||..:|....|.  :...::..||..:.|...
Yeast   284 NKKKKFKLSDDDSDIENDNDSDDAINRLVRQ--QDKDQAHLAHGL--KNLLINDDDDYLETRTNS 344

  Fly   437 IRRCSSLKTGKTPPGTPGRKKIVRFADVLGLDLADVKTFLDEIPTIPKSAFEDLEILESEPPLQL 501
            .:..::|..|.:       |:||...:         |.|                      |: |
Yeast   345 AKSGANLFIGNS-------KRIVGLYN---------KNF----------------------PI-L 370

  Fly   502 GPKSDKLLMPLFQQPGGLPKFLDAVREKQVSL-ENAAVTDNINQTISGSVRVRNLDFHKSVHIRY 565
            ..::.|.|.        |..||:..|.:.|.| |...:|...|..|.|.|.|:|:.|.|.:.:||
Yeast   371 SDRNRKSLK--------LNIFLNLSRGRPVFLQEITLLTGFHNMVIIGKVFVKNIYFDKKIIVRY 427

  Fly   566 SLDGWRSYADLQANYVENSCDGF-----SDIFTFVLFGNSLH--------VGQRLEFAVRFQCKG 617
            :.|.||::.:.:..|..|: :|.     .|||.|.:  :.:|        :.| |||.:::...|
Yeast   428 TWDAWRTFHESECVYFSNA-NGILPGSNMDIFKFSI--DDIHNPNDKDSNISQ-LEFCIQYLTWG 488

  Fly   618 -----QQFWDNNYGANYCFQCLPSSTHT 640
                 :::||||..|||....:.:.|.|
Yeast   489 VDRSRKEYWDNNDSANYKIDVVTNETRT 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gbs-76A	NP_649104.1	PRK02224	<208..>412	CDD:179385	51/279 (18%)
		PBD_PPP1R3	<434..475	CDD:455118	6/40 (15%)
		CBM_21	527..629	CDD:427265	36/120 (30%)
PIG2	NP_012219.3	CBM_21	388..507	CDD:427265	38/122 (31%)