Protein Alignment Gbs-76A and PPP1R3G

DIOPT Version :10

• Sequence 1: NP_649104.1
• Gene: Gbs-76A / 40102
• FlyBaseID: FBgn0036862
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001138587.1
• Gene: PPP1R3G / 648791
• HGNCID: 14945
• Length: 358
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 69/230 - (30%)
• Similarity: 96/230 - (41%)
• Gaps: 67/230 - (29%)

  Fly   456 KKIVRFADVLGLDLADVKTFLD-EIPTIPKSAF----------EDLEILES-------EPPLQLG 502
            ||.|:|||.|||.||.||.|.: |.|.:|.:..          ||||.|..       ..||...
Human   129 KKRVQFADTLGLSLASVKHFSEAEEPQVPPAVLSRLRSFPMRAEDLEQLGGLLAAAAVAAPLSAP 193

  Fly   503 PKSDKLLMPLFQQPGGLPK-FLDAVREKQVSLENAAVTDNINQTISGSVRVRNLDFHKSVHIRYS 566
            |..   |.||||.||  |. ..:.::.::|.||....:......:.||.||.:....::|.:||:
Human   194 PSR---LRPLFQLPG--PSAAAERLQRQRVCLERVQCSTASGAEVKGSGRVLSCPGPRAVTVRYT 253

  Fly   567 LDGWRSY----ADLQANYVE----NSCDGFS-------------DIFTFVLF------------- 597
            ...|||:    |:||...:|    .:..|.|             :.|.|.|.
Human   254 FTEWRSFLDVPAELQPEPLEPQQPEAPSGASEPGSGDAKKEPGAECFHFSLCLPPGLQPEDEEDA 318

  Fly   598 ---GNSLHVGQRLEFAVRFQCKGQQFWDNNYGANY 629
               |.::|      |||.::|...::||||.||||
Human   319 DERGVAVH------FAVCYRCAQGEYWDNNAGANY 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gbs-76A	NP_649104.1	PRK02224	<208..>412	CDD:179385
		PBD_PPP1R3	<434..475	CDD:455118	13/18 (72%)
		CBM_21	527..629	CDD:427265	34/138 (25%)
PPP1R3G	NP_001138587.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71
		PBD_PPP1R3	127..153	CDD:455118	14/23 (61%)
		CBM_21	212..349	CDD:427265	36/142 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..295		3/24 (13%)