DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14086 and Tmem72

DIOPT Version :9

Sequence 1:	NP_649102.3	Gene:	CG14086 / 40100	FlyBaseID:	FBgn0036860	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_848883.2	Gene:	Tmem72 / 319776	MGIID:	2442707	Length:	275	Species:	Mus musculus

Alignment Length:	179	Identity:	40/179 - (22%)
Similarity:	74/179 - (41%)	Gaps:	26/179 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 RVFGLLTSFVICGVGVDVYMHGYRAGL--YIVFSAVLVMFIEIKWLVTIFLQL--QCAEDNYQRR 94
            |:.|:.|:.|:.|||.:.::.|....|  |::|:.|.:...|..:.|...|.:  :|...:...|
Mouse    15 RLLGIATAAVLIGVGTETFLRGRFKSLAFYLLFTGVTISVCEGTYFVAQLLAICFKCQPGSLAHR 79

  Fly    95 SCSCLACWRLSAICGGWRPTPVYAVIGICLILYPHNLWLSYVAGMFLILLGLLRLCTLLRFSASK 159
            :.. .|.|     .|.::....|.::.:...|:|..:|...:.|..||:.||    .....|..|
Mouse    80 AKE-RAHW-----LGCFQKFLAYMLLSVACFLHPVLVWHVTIPGSMLIITGL----AYFLLSKRK 134

  Fly   160 EEGLLPQCDFEKVSSFVDTMEDDFAEIGATQAGLD-------EEAEEEG 201
            ::...|:     |:...:...|..:.:.:|....|       .||.:||
Mouse   135 KKKAAPE-----VAPPTEQYTDPSSSVVSTTGSGDTEQTYTFHEAFKEG 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14086	NP_649102.3	TMEM72	29..>138	CDD:292672	24/107 (22%)
Tmem72	NP_848883.2	TMEM72	2..189	CDD:292672	40/179 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	139..162		4/27 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	235..264
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR28474
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100