Protein Alignment CG14085 and LOC1269997

DIOPT Version :10

• Sequence 1: NP_649101.2
• Gene: CG14085 / 40099
• FlyBaseID: FBgn0036859
• Length: 874
• Species: Drosophila melanogaster
• Sequence 2: XP_308652.4
• Gene: LOC1269997 / 1269997
• VectorBaseID: AGAMI1_011112
• Length: 894
• Species: Anopheles gambiae
• Alignment Length: 901
• Identity: 489/901 - (54%)
• Similarity: 640/901 - (71%)
• Gaps: 42/901 - (4%)

  Fly     1 MEVLEEGNLMDRVPILLQRDLEFYQTHQRVLQEPICSGVVGGKLDFPRYASFAAIKLIRWWEDEY 65
            |||:||||||||:||||||||::|:.:|:||||.||:|||||||||||.||||::|::.|.||||
Mosquito     1 MEVMEEGNLMDRIPILLQRDLQYYEANQKVLQEDICAGVVGGKLDFPRSASFASVKIVIWLEDEY 65

  Fly    66 FASYRKPSGLL--------HTEKEMNEGDFSSVTVKTSDPDKFVQLVTKSADLLLEHIHRLSQES 122
            :|:|||.||||        |..||..|.......||:|||:|||.||:||.|.||||||.||||:
Mosquito    66 YAAYRKNSGLLHLADALQDHQTKEPEEAAGCGGIVKSSDPEKFVILVSKSVDNLLEHIHTLSQEA 130

  Fly   123 LDHADLSVLTATIGAASLVKNSLSVYMQAATTTICPPKGDEKGGALKLSFKQYSQMSEALAERLL 187
            ||||||:|||||||||:||||||.|::|..|..:||||||||||:||||:||||:|:||||||||
Mosquito   131 LDHADLTVLTATIGAAALVKNSLFVWLQCVTKNVCPPKGDEKGGSLKLSYKQYSEMTEALAERLL 195

  Fly   188 DLHCRLLLLYIMQDADCLHWEDTQPFFESERGSYTVQMWWHYMRGSQTDLWNSVPPKMAQKIFAG 252
            |||||||.|||:|||||||||...|||||||||||:||||.||:|::.||||||||.|||::|||
Mosquito   196 DLHCRLLTLYIIQDADCLHWESPHPFFESERGSYTIQMWWLYMQGTKQDLWNSVPPTMAQRVFAG 260

  Fly   253 MLNETLSVLTVRYTQIVTSVARSTLHLVDICNMLLCIAELLPHICESGEAYVGLQLSNQSVIIRD 317
            ||||||:||||||||.|.|.|||.|.|||:.|:|||:.||||.||.:|||:|||.|.:||.||||
Mosquito   261 MLNETLTVLTVRYTQTVPSRARSPLLLVDVSNVLLCVCELLPAICANGEAFVGLNLPSQSKIIRD 325

  Fly   318 IHAKCKELFYCLLLRGSPLGVLSKVFRKGLD-NMEMFSSRHGLPSAWIIFALPRYFPKEQSCQWV 381
            |||||:|||.||||||.|||.|.|:.:||:. .:.||..|.||...|.||.:||.||...:..|.
Mosquito   326 IHAKCQELFCCLLLRGIPLGALYKIAKKGVQGGIAMFGQRQGLIVPWTIFTMPRLFPPNLNAHWA 390

  Fly   382 TEFSDLSTNTAISLDLRVLLAFPEADWSYLLKILLMRDAYLTGIIMRHLMQYLPSSENFKNVAKI 446
            ...|:|.|:||::|:|:||||.|:|:|..|||:||||:|:|:.:|..||::.|||.:||...|:.
Mosquito   391 ARCSELPTSTALTLELKVLLAAPQANWWLLLKVLLMREAHLSSLIFHHLIRNLPSCDNFIPSARQ 455

  Fly   447 SFTSAEGAPQKCEAFLCRGECFNVTDSIAGDIDPVGQSNYQIVLSLTYLVVAVGKAVDIKSCLIK 511
            ...:.:...:|||.|||..||.::........||:||||||:::.|||:|:..||..||...||.
Mosquito   456 PSVNRDCLSKKCEGFLCGLECNDIVQWALEQNDPIGQSNYQVLMGLTYIVIMAGKTSDINKTLIS 520

  Fly   512 TLEEHAIAGWSDCLDKRQVWNQKRTPWLEAIMHFMYPVLDCVVDMLVNAVENGASMYQAMSLALT 576
            .||:..:..|:.|||:||||||||.||||||:|.:||:|..||.|||:||:..|||||||||:|:
Mosquito   521 ALEKSKMNDWASCLDRRQVWNQKRPPWLEAILHLIYPILGPVVHMLVSAVQTTASMYQAMSLSLS 585

  Fly   577 CVSEIWDCLPEGLYKIASLLQDIIPVSTRPLGDSVLLQVVFAALYTELIKTAEMYEQAKDLDKAA 641
            |.||:|||:|:..|.:.:.|.:|:|...||||||||:|:::.|||::|::.||...:|:..::||
Mosquito   586 CFSEMWDCIPDCFYTVTNCLAEILPAEIRPLGDSVLIQLLYIALYSKLLEVAETEAEAEAKEQAA 650

  Fly   642 -------------------------ICYSISEAICSIDEDDKHTDQIELFLKQAKESINLDTDFG 681
                                     ||.:::||||.||||:|||:||...:.||:||   ....|
Mosquito   651 SGTGPTEASPPVAPVSTINMKPKSVICQTLAEAICFIDEDNKHTEQINSLISQARES---QRSMG 712

  Fly   682 GTAGSNNRGAGGMSAVSTIKMDDLALTNAESDRLSHSPPNNYAMELDVGIADYIAEVLVSDVLTT 746
            ......:...|..|..||.::||:     |:.....:|......|.||..|:||||:||||||.|
Mosquito   713 VLESEIDDAVGLASFASTSRVDDV-----EAFLRQTTPSVRSEEEFDVENAEYIAEMLVSDVLVT 772

  Fly   747 NIGKQALKVVYNYLKFNKDWLLEQLGTGDNDPSPFQGIQGQNIKEAKTSVLRSMFFIGNTPFDQL 811
            ::||.::|::|.|::.|.||:|:|||..|.:.:|.|...||:|:|.:.:::..||.||:..||||
Mosquito   773 SVGKLSMKMLYQYIRKNFDWILQQLGVSDVEQNPLQPSPGQSIREQQQTLIDLMFHIGHRSFDQL 837

  Fly   812 LTGSLKIDYVSWLQMPLSLNPERTCLHLNRRCDFQEDAKLSLPEVAMVAGITKIMK 867
            |:|.|.|||..|.|.|:|::.|:..|.:.:|.:|||.||||:.|..||:.||..:|
Mosquito   838 LSGGLDIDYTKWFQTPMSMSVEKAWLQVCQRWEFQEGAKLSVHEALMVSFITTQLK 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14085	NP_649101.2	DUF4495	99..430	CDD:464363	224/331 (68%)
LOC1269997	XP_308652.4	DUF4495	107..439	CDD:464363	224/331 (68%)