DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14088 and CG18754

DIOPT Version :9

Sequence 1:	NP_649100.2	Gene:	CG14088 / 40098	FlyBaseID:	FBgn0036858	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	242	Identity:	59/242 - (24%)
Similarity:	96/242 - (39%)	Gaps:	62/242 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 PWTAILHHFGRIVGVGTLIHERFILTDVHCGDSIG--------VIRA-RLGE-----------YG 89
            ||..:|.:..|:    :||  |::||..||  .||        |::: ||||           ..
  Fly   118 PWMVLLLYENRL----SLI--RYVLTAAHC--VIGGYLTQNDLVLKSVRLGESTTDCITSESRCP 174

  Fly    90 RIGSELAEDHIVAAFFSNANFNPETQANNMGLMKLLRTVVYKEHIIPVCI------LMDSRMQTF 148
            .:..|:.:..:...|.|:..    |..|::.|::|...|.|.:.|.|:|:      |.|..:|.
  Fly   175 HLDVEVGQTTVHQGFTSSGG----TYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLNLQI- 234

  Fly   149 ADELDYFNGTTWKNSDKSPMLRSKTV-IRMPQACGKLDH-------GQFCA-GHKDLDSCDEPSG 204
                     :.|..:..|..|.:.|| .|.|..|  |:.       .|.|| |.:..|:|...||
  Fly   235 ---------SGWDPTKSSQTLITSTVKERNPADC--LNRYPSFRSASQVCAGGQRKGDTCAGISG 288

  Fly   205 AALTREIDYIGPNRTVLFGIANSVEVKCSNS---RTYTDVVQLHQWI 248
            :.:...:.........|.|||:..:..|.::   ..||.:....:||
  Fly   289 SPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14088	NP_649100.2	Tryp_SPc	42..251	CDD:304450	59/242 (24%)
CG14088	NP_649100.2	Tryp_SPc	42..248	CDD:214473	57/240 (24%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	59/242 (24%)
		Tryp_SPc	108..335	CDD:214473	57/240 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010