DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14088 and CG3505

DIOPT Version :9

Sequence 1:	NP_649100.2	Gene:	CG14088 / 40098	FlyBaseID:	FBgn0036858	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	62/284 - (21%)
Similarity:	102/284 - (35%)	Gaps:	69/284 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SGTGSA--QFLGNICGERRDGLSPDI-----VGPWTAI----------LHHFGRIVGVGTLIHER 66
            :|.|:.  ..|.:.||:.|...|.|.     ..||.|:          :|..|     |.||.:|
  Fly    86 AGLGALTHPLLPSDCGKVRWQRSNDTDTRIREFPWLALIEYTRGNQEKIHACG-----GVLISDR 145

  Fly    67 FILTDVHC-----GDSIGVIRARLGEYG---------RIGSELA------EDHIVAAFFSNANFN 111
            ::||..||     ..::.:...||||:.         ...|::|      :|..:.....:..:|
  Fly   146 YVLTAAHCVAQAATSNLQITAVRLGEWDTSTNPDCQYHEDSKVADCAPPYQDIAIEELLPHPLYN 210

  Fly   112 --PETQANNMGLMKLLRTVVYKEHIIPVCILMDSRMQTFADELD--YFNGTTWKNSDKSPMLRSK 172
              ..||.|::.|::|.......:.:.|:|:   ...|..||||:  ......|:.|....|.:..
  Fly   211 RTDRTQINDIALVRLASPAKLNDFVQPICL---PNKQLRADELEDLVTEVAGWQASSSQRMRKGY 272

  Fly   173 TVIRMPQACG--------KLDHGQFCAGHKDLDSCDEPSGAALT--REIDYIGPNRTVLFGIANS 227
            ..|...:.|.        ::...:.| |..:...|...:|..|.  :...|:      |.|:.:.
  Fly   273 VTISSIEECQRKYASQQLRIQASKLC-GLTNSQECYGNAGGPLMLFKNDGYL------LGGLVSF 330

  Fly   228 VEVKCSN---SRTYTDVVQLHQWI 248
            ..|.|.|   ...||.|.....||
  Fly   331 GPVPCPNPDWPDVYTRVASYIDWI 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14088	NP_649100.2	Tryp_SPc	42..251	CDD:304450	54/259 (21%)
CG14088	NP_649100.2	Tryp_SPc	42..248	CDD:214473	52/257 (20%)
CG3505	NP_650380.2	CLIP	30..82	CDD:288855
		Tryp_SPc	111..356	CDD:238113	54/259 (21%)
		Tryp_SPc	111..354	CDD:214473	52/257 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010