Protein Alignment Aldh7A1 and MSC7

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_011904.1
• Gene: MSC7 / 856434
• SGDID: S000001081
• Length: 644
• Species: Saccharomyces cerevisiae
• Alignment Length: 552
• Identity: 112/552 - (20%)
• Similarity: 210/552 - (38%)
• Gaps: 94/552 - (17%)

  Fly    27 SSSYLIDQPEYSFLKELGLERDNPGVYSGQWQGRGPSVTS------------YDPGTGQPIAKVR 79
            ||||          |.:......|......|:|:....|:            :.|.|||.:....
Yeast    73 SSSY----------KPVKFSLPAPEAAQNNWKGKRSVSTNIWNPEEPNFIQCHCPATGQYLGSFP 127

  Fly    80 QGNVQELEHTIGLAVEAYKQWRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGK-IYSEGQG 143
            .....:::..:..|.:|...|.......|..::..:.|.:...::.:.::...:.|| :.....|
Yeast   128 SKTEADIDEMVSKAGKAQSTWGNSDFSRRLRVLASLHDYILNNQDLIARVACRDSGKTMLDASMG 192

  Fly   144 EVQEFIDICDYAVG-----------------LSRIYSGQLINSERADHSILEAWRPLGVVGVISA 191
            |:...::...:.:.                 ..:.|.|..|..|           ||||:..|.:
Yeast   193 EILVTLEKIQWTIKHGQRALQPSRRPGPTNFFMKWYKGAEIRYE-----------PLGVISSIVS 246

  Fly   192 YNFP-NAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRR-----NNLPPVVTLC-- 248
            :|:| :.:.|...| ||.|||:::.|.:...    |.:::...|::|:     :..|.:|.||
Yeast   247 WNYPFHNLLGPIIA-ALFTGNAIVVKCSEQV----VWSSEFFVELIRKCLEACDEDPDLVQLCYC 306

  Fly   249 ---QGGTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVILELGGNNALIIDESANVKM 310
               ....|......:......::|.||......:.....:....|::||||.:|.|:.:||....
Yeast   307 LPPTENDDSANYFTSHPGFKHITFIGSQPVAHYILKCAAKSLTPVVVELGGKDAFIVLDSAKNLD 371

  Fly   311 ALDAALF-GCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLE--AQTLVGPVH 372
            ||.:.:. |...:|||.|....|:||.::.:|..||.|..:......:.|..::  ....:|.:.
Yeast   372 ALSSIIMRGTFQSSGQNCIGIERVIVSKENYDDLVKILNDRMTANPLRQGSDIDHLENVDMGAMI 436

  Fly   373 TQQNVENYKAAIAEAKSLGGTVAFGGNVIQR----DGFYVEPTVITGLPHDASVVHRETFAPIVY 433
            :....:..:|.:.:|.:.|..:..||:..:.    .|.|.:||::..:..:..:...|.|.||:.
Yeast   437 SDNRFDELEALVKDAVAKGARLLQGGSRFKHPKYPQGHYFQPTLLVDVTPEMKIAQNEVFGPILV 501

  Fly   434 ILKAKNVDQAIEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGG----- 493
            ::||||.|..::..|....||..::|           ||...:|..|..:..|....|..
Yeast   502 MMKAKNTDHCVQLANSAPFGLGGSVF-----------GADIKECNYVANSLQTGNVAINDFATFY 555

  Fly   494 ----AFGGEKATGGGRESGSDAWKQYCKRATI 521
                .|||...:|.|:..|.:.....|...::
Yeast   556 VCQLPFGGINGSGYGKFGGEEGLLGLCNAKSV 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	106/528 (20%)
MSC7	NP_011904.1	ALDH_F15-22	115..590	CDD:143416	103/500 (21%)