Protein Alignment Aldh7A1 and Aldh1b1

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_082546.1
• Gene: Aldh1b1 / 72535
• MGIID: 1919785
• Length: 519
• Species: Mus musculus
• Alignment Length: 532
• Identity: 152/532 - (28%)
• Similarity: 254/532 - (47%)
• Gaps: 40/532 - (7%)

  Fly     9 SKLALPRRLVTQ--TASYSSSSSY--LIDQPEYSFLKELGLERDNPGVYSGQWQGRGPSVT--SY 67
            ::|.|||.|..|  |.|||::::.  .|..||..:         |....:.:|.......|  :.
Mouse     4 ARLLLPRLLCLQGRTTSYSTAAALPNPIPNPEICY---------NKLFINNEWHDAVSKKTFPTV 59

  Fly    68 DPGTGQPIAKVRQGNVQELEHTIGLAVEAYK---QWRQVPAPVRGEIVRQIGDELRKYKEPLGKL 129
            :|.||:.|..|.:|:..:::..:..|.||::   .||::.|..||.::.::.|.:.:.:..|..|
Mouse    60 NPTTGEVIGHVAEGDRADVDLAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASL 124

  Fly   130 VSLEVGKIYSEGQG-EVQEFIDICDYAVGLSRIYSGQLINSERADHSILEAWRPLGVVGVISAYN 193
            .:|:.||.:.|... ::.|.|.:..|..|.:..:.|:.|..: .:|.......|:||.|.|..:|
Mouse   125 ETLDNGKPFQESYVLDLDEVIKVYRYFAGWADKWHGKTIPMD-GEHFCFTRHEPVGVCGQIIPWN 188

  Fly   194 FPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VVTLCQG-GTDVGQ 256
            ||..:.||..|.||.|||:|:.|.|..|||.::    .:|.:::....|| ||.:..| |...|.
Mouse   189 FPLVMQGWKLAPALATGNTVVMKVAEQTPLSAL----YLASLIKEAGFPPGVVNIITGYGPTAGA 249

  Fly   257 TLVADKRVNLVSFTGSCQTGRDVGVEVQRRFG-----KVILELGGNNALIIDESANVKMALDAAL 316
            .:.....|:.|:||||    .:||..:|:..|     :|.|||||.:..|:...|:::.|:|...
Mouse   250 AIAQHMDVDKVAFTGS----TEVGHLIQKAAGESNLKRVTLELGGKSPSIVLADADMEHAVDQCH 310

  Fly   317 FGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYK 381
            .......||.|....|..|.|.::.:|::..|.|.||  .|:|:..|..|..||...::..|...
Mouse   311 EALFFNMGQCCCAGSRTFVEESIYREFLERTVEKAKQ--RKVGNPFELDTQQGPQVDKEQFERIL 373

  Fly   382 AAIAEAKSLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEW 446
            ..|...:..|..:..||..:...||:::|||...:.....:...|.|.|:..:.|.|.:::.|:.
Mouse   374 GYIRLGQKEGAKLLCGGERLGERGFFIKPTVFGDVQDGMRIAKEEIFGPVQPLFKFKKIEEVIQR 438

  Fly   447 NNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRESGSDA 511
            .|....||::|:||.::.:|..:  .:....|.|.:| |.|.......|||.|.:|.|||.|.|.
Mouse   439 ANNTRYGLAAAVFTRDLDKAIYF--TQALQAGTVWVN-TYNIVTCHTPFGGFKESGNGRELGEDG 500

  Fly   512 WKQYCKRATITV 523
            .:.|.:..|:|:
Mouse   501 LRAYTEVKTVTI 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	138/486 (28%)
Aldh1b1	NP_082546.1	ALDH_F1AB_F2_RALDH1	33..513	CDD:143459	141/503 (28%)