Protein Alignment Aldh7A1 and Aldh8a1

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001178017.2
• Gene: Aldh8a1 / 685750
• RGDID: 1590218
• Length: 487
• Species: Rattus norvegicus
• Alignment Length: 478
• Identity: 130/478 - (27%)
• Similarity: 233/478 - (48%)
• Gaps: 31/478 - (6%)

  Fly    64 VTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYKQWRQVPAPVRGEIVRQIGDELRKYKEPLGK 128
            :.||||.||:...||.....:|:|..:..|.||:..|.......|..|:.::.|.|.:..|.|.:
  Rat    25 IDSYDPSTGEVYCKVPNSGKEEIEVAVQAAREAFPAWSSRSPQERSLILNRVADVLEQSLEELAQ 89

  Fly   129 LVSLEVGKIYSEGQGEVQEFIDICDYAVGLSRIYSGQLIN--SERADHSILEAWR-----PLGVV 186
            ..|.:.||..:     :...:||....:.. |.::..:.:  |:..:.|.|....     |:|:.
  Rat    90 AESKDQGKTLT-----LARTMDIPRSVLNF-RFFASSIQHHVSDCTEMSHLGCMHYTVRTPVGIA 148

  Fly   187 GVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VVTLCQG 250
            |:||.:|.|..:..|..|.|:..||:|:.|  || .|.|| |..:..::|.:..:|| |:.:..|
  Rat   149 GLISPWNLPLYLLTWKIAPAIAAGNTVIAK--PS-ELTSV-TAWMFCKLLDKAGVPPGVINVVFG 209

  Fly   251 -GTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVILELGGNNALIIDESANVKMALDA 314
             |..||:.||:...|.::|||||..|...:.........|:.|||||.|..||.|.||::..:.|
  Rat   210 TGPRVGEALVSHPEVPVISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLEECIPA 274

  Fly   315 ALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVEN 379
            .:.......|:.|..|.||.|...::::|:|..|...::.  |:|...:....:|.:.::.::|.
  Rat   275 TVRSSFANQGEICLCTSRIFVQRSIYNEFLKRFVEATRKW--KVGIPSDPSANMGALISKAHLEK 337

  Fly   380 YKAAIAEAKSLGGTVAFGGNVIQ-------RDGFYVEPTVITGLPHDASVVHRETFAPIVYILKA 437
            .::.:.:|.:.|..:..|..|.|       :.|:::.|||||.:..::..:..|.|.|:..::..
  Rat   338 VRSYVTKAHAEGAKILCGEGVDQLSLPLRNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPF 402

  Fly   438 KNVDQAIEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATG 502
            .:.::.|...|.|:.||.:.::::::|:..:  .||....|:|..|.... .|:...|||.|::|
  Rat   403 DSEEEVIARANGVKYGLGATVWSKDVGRIHR--VAKRLQSGLVWTNCWLI-RELNLPFGGMKSSG 464

  Fly   503 GGRESGSDAWKQYCKRATITVNH 525
            .|||...|::..:.:..|||:.:
  Rat   465 IGREGAKDSYDFFTEIKTITIKY 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	130/478 (27%)
Aldh8a1	NP_001178017.2	ALDH_F8_HMSADH	27..485	CDD:143412	129/472 (27%)