Protein Alignment Aldh7A1 and Aldh1a3

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_444310.3
• Gene: Aldh1a3 / 56847
• MGIID: 1861722
• Length: 512
• Species: Mus musculus
• Alignment Length: 516
• Identity: 146/516 - (28%)
• Similarity: 252/516 - (48%)
• Gaps: 56/516 - (10%)

  Fly    49 NPGVYSGQWQGRGPSV-----------------------------TSYDPGTGQPIAKVRQGNVQ 84
            |..|.:||..|:.|::                             .:|:|.|.:.|.:|.:|:..
Mouse     5 NGAVENGQPDGKPPALPRPIRNLEVKFTKIFINNDWHESKSGRKFATYNPSTLEKICEVEEGDKP 69

  Fly    85 ELEHTIGLAVEAYKQ---WRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGK-----IYSEG 141
            :::..:..|..|:::   ||::.|..||:::.|:.|.:.:.:..|..|.:::.||     .:.:.
Mouse    70 DVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLVERDRAILATLETMDTGKPFLHAFFVDL 134

  Fly   142 QGEVQEFIDICDYAVGLSRIYSGQLINSERADHSI-LEAWRPLGVVGVISAYNFPNAVFGWNAAI 205
            :|.::.|    .|..|.:....|:.|.::  |:.: .....|:||.|.|:.:|||..:..|..|.
Mouse   135 EGCIKTF----RYFAGWADKIQGRTIPTD--DNVVCFTRHEPIGVCGAITPWNFPLLMLAWKLAP 193

  Fly   206 ALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VVTLCQG-GTDVGQTLVADKRVNLVS 268
            ||..||:|:.|.|..|||.::....::.||    ..|| ||.:..| |..||..:.:..::|.::
Mouse   194 ALCCGNTVVLKPAEQTPLTALYLASLIKEV----GFPPGVVNIVPGFGPTVGAAISSHPQINKIA 254

  Fly   269 FTGSCQTGRDVGVEVQR-RFGKVILELGGNNALIIDESANVKMALDAALFGCIGTSGQRCTTTRR 332
            ||||.:.|:.|.....| ...:|.|||||.|..|:...|::.:|::.|..|.....||.||...|
Mouse   255 FTGSTEVGKLVREAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASR 319

  Fly   333 IIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKSLGGTVAFG 397
            :.|.|:::.:||:..|...|:  ..:|...:|:|..||...|:..:.....|...|..|..:..|
Mouse   320 VFVEEQVYGEFVRRSVEFAKK--RPVGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECG 382

  Fly   398 GNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGLSSAIFTEN 462
            |:.::..|.:::|||.:.:..:..:...|.|.|:..|||.||:::.|:..|..:.||::|:||:|
Mouse   383 GSAMEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKN 447

  Fly   463 IGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQYCKRATITV 523
            :.:|.|...|..|  |.|.|| ..|.......|||.|.:|.|||.|..|..:|.:..|:|:
Mouse   448 LDKALKLAAALES--GTVWIN-CYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTI 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	145/514 (28%)
Aldh1a3	NP_444310.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		6/16 (38%)
		ALDH_F1AB_F2_RALDH1	26..506	CDD:143459	140/495 (28%)