DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Aldh7A1 and aldh16a1

DIOPT Version :9

Sequence 1:	NP_649099.1	Gene:	Aldh7A1 / 40097	FlyBaseID:	FBgn0036857	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001073423.2	Gene:	aldh16a1 / 492710	ZFINID:	ZDB-GENE-070112-2062	Length:	795	Species:	Danio rerio

Alignment Length:	439	Identity:	91/439 - (20%)
Similarity:	171/439 - (38%)	Gaps:	64/439 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 QELEHTIGLAVEAYKQWRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGKIYSEGQGEVQEF 148
            :::...:..|...:|.|.|:....|.:::.::...|:::.:.:.::..|      |:........
Zfish    75 EDVASAVSSAAAGFKTWSQLSCYQRAKVLLKLPGVLQRHSQCVSEVCEL------SQSTTSPAVL 133

  Fly   149 IDICDYAVGLSRIYSGQLINSERADHSILEAWRPLGVVGVI-----SAYNFPNAVFGWNAAIALT 208
            |.:..|....:::...:           :..|.|.|||.|:     |.|.....|..     ||.
Zfish   134 IRLAQYYASWAQLRDTR-----------MPEWSPQGVVTVVVSDDCSVYFLLLKVLP-----ALA 182

  Fly   209 TGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPPVVTLCQGGTD--VGQTLVADKRVNLVSFTG 271
            .||:|:.....:|.|..:    ::|::.....:|..|.....|::  :...:..:.:||.::|:|
Zfish   183 MGNAVIVVPGKTTALPGL----LLAQLFMEAGMPAGVLNVLTGSEASLAAKMAQNPQVNYLTFSG 243

  Fly   272 SCQTGRDV-----GVEVQRRFGKVILELGGNNALIIDESANVKMALDAALFGCIGTSGQRCTTTR 331
            ..|||..|     |..|...|.   |........||.|||:    ||:|:.|.|..:.::....:
Zfish   244 CRQTGEAVAKAAAGWGVPMTFS---LSSSSVCPFIIFESAD----LDSAVDGVIELAFKKKRDFQ 301

  Fly   332 RII-VHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKSLGGTVA 395
            .:: |.|.:.|..|..|..:..::...            |:.:..:.....|||.||:..|.|:.
Zfish   302 WVLCVQESVLDSVVARLKTRMAEMKGV------------PLASDPDRSIIDAAIQEAQQQGATLI 354

  Fly   396 FGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGLSSAIFT 460
            .........|.| .|||:.||......|......|::.::..::..:.:...|....|.:::|:|
Zfish   355 QSCPPASTGGLY-PPTVLCGLAPSCESVISPPPGPVLPLITFRSSAEGVTLGNHSPHGQAASIWT 418

  Fly   461 ENIGQAFKWIGAKGSDCGIVNIN---TTTNGAEIGGAFGGEKATGGGRE 506
            |::..|.:  .||....|.|.:|   .......:.|.......|.||||
Zfish   419 EDLTLALE--SAKSLCVGSVWVNCHSVMDPALPLCGRRDSGNCTDGGRE 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	91/439 (21%)
aldh16a1	NP_001073423.2	ALDH-SF	18..470	CDD:299846	91/439 (21%)
aldh16a1	NP_001073423.2	AdhE	514..>755	CDD:223944
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900