Protein Alignment Aldh7A1 and Aldh1l2

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001178707.2
• Gene: Aldh1l2 / 299699
• RGDID: 1309458
• Length: 923
• Species: Rattus norvegicus
• Alignment Length: 494
• Identity: 136/494 - (27%)
• Similarity: 237/494 - (47%)
• Gaps: 56/494 - (11%)

  Fly    61 GPSVTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYK--QWRQVPAPVRGEIVRQIGDELRKYK 123
            |.:..:.:|..|..:.:|...::.:::..:..|.:|::  :|.::.|..||.::.::.|.:.:.:
  Rat   457 GETYATINPTDGTTLCRVSYASLADVDRAVAAAKDAFENGEWGRMNARDRGRLMYRLADLMEENQ 521

  Fly   124 EPLGKLVSLEVGKIYSEGQG-----EVQEF---------IDICDYAVGLSRIYSGQLINSERADH 174
            |.|..:.:|:.|.:|:....     .||.|         |.:.......:||:....::||
  Rat   522 EELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQVTKEPENQARIHDTLGMSSE---- 582

  Fly   175 SILEAWRPLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRN 239
                  .|..|..:|..:|:|..:..|.:|..|..||:::.|.|..|||.::.    .||:..:.
  Rat   583 ------EPKVVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALK----FAELTVKA 637

  Fly   240 NLPP-VVTLCQG-GTDVGQTLVADKRVNLVSFTGSCQTGRDVGVE-VQRRFGKVILELGGNNALI 301
            ..|. |:.:..| |...||.|.....:..:.||||...|:.:... ......||.|||||.:.||
  Rat   638 GFPKGVINIIPGSGGVAGQRLSQHPDIRKLGFTGSTSVGKQIMKSCAVSNLKKVSLELGGKSPLI 702

  Fly   302 IDESAN----VKMALDAALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQL 362
            |.....    |:|.:.|..|    ..|:.|....|:.|.|.:||:||..:|.:.|::  |||..|
  Rat   703 IFSDCELDKAVRMGMGAVFF----NKGENCIAAGRLFVEEAIHDEFVTRVVEEIKKM--KIGDPL 761

  Fly   363 EAQTLVGP----VHTQQNVENYKAAIAEAKSLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVV 423
            :..|..||    .|.::.::..:..:.|    |.|:.:||..:||.||::||||.||:.....:.
  Rat   762 DRSTDHGPQNHKAHLEKLLQYCETGVKE----GATLVYGGRQVQRPGFFMEPTVFTGVEDHMYLA 822

  Fly   424 HRETFAPIVYILKAKN--VDQAIEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTT 486
            ..|:|.||:.|.|.:|  :|..::..|..|.||:|.:||.:|.:|. ::..: .:.|.|.|| |.
  Rat   823 KEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDISKAM-YVSDR-LEAGTVFIN-TY 884

  Fly   487 NGAEIGGAFGGEKATGGGRESGSDAWKQYCKRATITVNH 525
            |..::...|||.|.:|.|::.|.:|..:|.|..|:|:.:
  Rat   885 NKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	136/494 (28%)
Aldh1l2	NP_001178707.2	FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731
		PP-binding	346..>390	CDD:425746
		ALDH_F1L_FTFDH	438..923	CDD:143458	136/492 (28%)