Protein Alignment Aldh7A1 and Aldh8a1

DIOPT Version :9

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_848828.1
• Gene: Aldh8a1 / 237320
• MGIID: 2653900
• Length: 487
• Species: Mus musculus
• Alignment Length: 484
• Identity: 126/484 - (26%)
• Similarity: 227/484 - (46%)
• Gaps: 43/484 - (8%)

  Fly    64 VTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYKQWRQVPAPVRGEIVRQIGDELRKYKEPLGK 128
            :.||||.||:...||.....:|:|..:..|.||:..|.......|..::.::.|.|.:..|.|.:
Mouse    25 IDSYDPSTGEVYCKVPNSGKEEIEAAVEAAREAFPAWSSRSPQERSLVLNRLADVLEQSLEELAQ 89

  Fly   129 LVSLEVGKIYSEGQGEVQEFIDICDYAVGLSRIYSGQLINSERADHSILEAWR------------ 181
            ..|.:.||..:     :...:||....:......|..|       |.:.|..:
Mouse    90 AESKDQGKTLT-----LARTMDIPRSVLNFRFFASSNL-------HHVSECTQMSHLGCMHYTVR 142

  Fly   182 -PLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-V 244
             |:|:.|:||.:|.|..:..|..|.|:..||:|:.|.:..|.:    |..:..::|.:..:|| |
Mouse   143 TPVGIAGLISPWNLPLYLLTWKIAPAIAAGNTVIAKPSEMTSV----TAWMFCKLLDKAGVPPGV 203

  Fly   245 VTLCQG-GTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVILELGGNNALIIDESANV 308
            :.:..| |..||:.||:...|.|:|||||..|...:.........|:.|||||.|..||.|.||:
Mouse   204 INIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANL 268

  Fly   309 KMALDAALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHT 373
            :..:.|.:.......|:.|..|.||.|...::.:|:|..|...::.  |:|...:....:|.:.:
Mouse   269 EECIPATVRSSFANQGEICLCTSRIFVQRSIYSEFLKRFVEATRKW--KVGVPSDPSANMGALIS 331

  Fly   374 QQNVENYKAAIAEAKSLGGTVAFGGNVIQ-------RDGFYVEPTVITGLPHDASVVHRETFAPI 431
            :.::|..::.:.:|::.|..:..|..|.|       :.|:::.|||||.:..::..:..|.|.|:
Mouse   332 KAHLEKVRSYVLKAQTEGARILCGEGVDQLSLPLRNQAGYFMLPTVITDIKDESRCMTEEIFGPV 396

  Fly   432 VYILKAKNVDQAIEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFG 496
            ..::...:.::.|...|.|..||::.::::::|:..:  .||....|:|..|.... .|:...||
Mouse   397 TCVVPFDSEEEVITRANSVRYGLAATVWSKDVGRIHR--VAKKLQSGLVWTNCWLI-RELNLPFG 458

  Fly   497 GEKATGGGRESGSDAWKQYCKRATITVNH 525
            |.|::|.|||...|::..:.:..|||:.:
Mouse   459 GMKSSGIGREGAKDSYDFFTEIKTITIKY 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	126/484 (26%)
Aldh8a1	NP_848828.1	ALDH_F8_HMSADH	27..485	CDD:143412	125/478 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900