Protein Alignment Aldh7A1 and ALDH3B1

DIOPT Version :9

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_000685.1
• Gene: ALDH3B1 / 221
• HGNCID: 410
• Length: 468
• Species: Homo sapiens
• Alignment Length: 459
• Identity: 114/459 - (24%)
• Similarity: 193/459 - (42%)
• Gaps: 101/459 - (22%)

  Fly    95 EAYKQWRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGKIYSEGQGEVQEFIDICDYAVGLS 159
            ||:...|..||..|...::.:|..|::.|:.|...::.::.|  |..:.||.|        |.:|
Human    13 EAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHK--SAFESEVSE--------VAIS 67

  Fly   160 RIYSGQLINSERADHSILEAW---------------------RPLGVVGVISAYNFPNAVFGWNA 203
            :   |::..:.|.    |.||                     .|.|:|.:|:.:|:|     .|.
Human    68 Q---GEVTLALRN----LRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYP-----LNL 120

  Fly   204 AI-----ALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPPVV------TLCQGGTDVGQT 257
            .:     ||..||.|:.|  ||.  :|....||:|||     ||..|      .:..|..:.||.
Human   121 TLVPLVGALAAGNCVVLK--PSE--ISKNVEKILAEV-----LPQYVDQSCFAVVLGGPQETGQL 176

  Fly   258 LVADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVILELGGNNALIIDESANVKMALDAALFGCIGT 322
            |  :.|.:.:.||||.:.|:.|.....:....|.|||||.|...:|::.:.:...:...:.....
Human   177 L--EHRFDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFN 239

  Fly   323 SGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKI-GHQLEAQTLVGPVHTQQNVENYKAAIAE 386
            :||.|.....::...::.::.:..|    :..|::. |...::...:|.:..|:..:..:|.
Human   240 AGQTCVAPDYVLCSPEMQERLLPAL----QSTITRFYGDDPQSSPNLGRIINQKQFQRLRAL--- 297

  Fly   387 AKSLG-GTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEV 450
               || |.||.||...:.|. |:.|||:..:.....|:..|.|.||:.|:..:::|:|||:.|..
Human   298 ---LGCGRVAIGGQSDESDR-YIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRR 358

  Fly   451 EQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGG-----------AFGGEKATGGG 504
            |:.|:...|: |..|..|.:           :..|::|...|.           .|||..|:|.|
Human   359 EKPLALYAFS-NSSQVVKRV-----------LTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMG 411

  Fly   505 RESG 508
            |..|
Human   412 RYHG 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	114/459 (25%)
ALDH3B1	NP_000685.1	ALDH_F3AB	6..447	CDD:143450	114/459 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900