Protein Alignment Aldh7A1 and ALDH1A1

DIOPT Version :9

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_000680.2
• Gene: ALDH1A1 / 216
• HGNCID: 402
• Length: 501
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 137/499 - (27%)
• Similarity: 232/499 - (46%)
• Gaps: 53/499 - (10%)

  Fly    54 SGQWQG--RGPSVTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYK---QWRQVPAPVRGEIVR 113
            :.:|..  .|.....::|.|.:.:.:|.:|:.::::..:..|.:|::   .||.:.|..||.::.
Human    26 NNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLY 90

  Fly   114 QIGDELRKYKEPLGKLVSLEVGKIYSEGQ-GEVQEFIDICDYAVGLSRIYSGQLINSERADHSIL 177
            ::.|.:.:.:..|..:.|:..||:||... .::...|....|..|.:....|:.|   ..|.:..
Human    91 KLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTI---PIDGNFF 152

  Fly   178 EAWR--PLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNN 240
            ...|  |:||.|.|..:|||..:..|....||:.||:|:.|.|..|||    |...||.:::...
Human   153 TYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPL----TALHVASLIKEAG 213

  Fly   241 LPP-VVTLCQG-GTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQRRFGK-----VILELGGNN 298
            .|| ||.:..| |...|..:.:...::.|:||||    .:||..::...||     |.|||||.:
Human   214 FPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGS----TEVGKLIKEAAGKSNLKRVTLELGGKS 274

  Fly   299 ALIIDESANVKMALDAALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLE 363
            ..|:...|::..|::.|..|.....||.|....||.|.|.::|:||:..|.:.|:.|  :|:.|.
Human   275 PCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYI--LGNPLT 337

  Fly   364 AQTLVGPVHTQQNVENYKAAIAEAKSLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETF 428
            .....||...::..:.....|...|..|..:..||......|::|:|||.:.:..:..:...|.|
Human   338 PGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIF 402

  Fly   429 APIVYILKAKNVDQAIEWNNEVEQGLSSAIFTENIGQAFK----------WIGAKGSDC-GIVNI 482
            .|:..|:|.|::|..|:..|....|||:.:||::|.:|..          |:     :| |:|:.
Human   403 GPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWV-----NCYGVVSA 462

  Fly   483 NTTTNGAEIGGAFGGEKATGGGRESGSDAWKQYCKRATITVNHS 526
            ..         .|||.|.:|.|||.|...:.:|.:..|:||..|
Human   463 QC---------PFGGFKMSGNGRELGEYGFHEYTEVKTVTVKIS 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	136/497 (27%)
ALDH1A1	NP_000680.2	ALDH_F1AB_F2_RALDH1	15..495	CDD:143459	135/495 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810