Protein Alignment Aldh7A1 and aldh1l2

DIOPT Version :9

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_002938116.1
• Gene: aldh1l2 / 100127737
• XenbaseID: XB-GENE-5820495
• Length: 922
• Species: Xenopus tropicalis
• Alignment Length: 602
• Identity: 162/602 - (26%)
• Similarity: 271/602 - (45%)
• Gaps: 104/602 - (17%)

  Fly     3 AQLRNISKLALPR-RLVTQTASYSSSSSYLIDQPEYSFLKEL-----GLERDNPGVY-------- 53
            :::|||.|..|.. .::..|..:..|.:..:|  ....::||     |||..|..||
 Frog   346 SEIRNIWKGILSNVSVIENTTDFFKSGAASMD--VVRLVEELKQKCEGLELQNEDVYMATTFEEF 408

  Fly    54 --------------------------------------SGQW--QGRGPSVTSYDPGTGQPIAKV 78
                                                  :||:  ...|.:..:.:|..|..|.||
 Frog   409 IQMVVRKLRGEDKEELVIDYASLNVNNMTVKMPYQCFINGQFADADNGKTYDTINPTDGSVICKV 473

  Fly    79 RQGNVQELEHTIGLAVEAYK--QWRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGKIYS-- 139
            ...:|.:::..:..|.:|::  :|.::.|..||.|:.::.|.:.:::|.|..:.:::.|.:|:
 Frog   474 AYCSVADVDKAVAAAKDAFENGEWGKMNARDRGRILYRLADLMEEHQEELATIEAIDSGAVYTLA 538

  Fly   140 ----EGQGEVQE---FIDICDYAVGLSRIYSGQLINSERADHSI-LEAWRPLGVVGVISAYNFPN 196
                .|. .||.   |...||...|     |...||..|.:.:: .....||||..::..:|:|.
 Frog   539 LKTHVGM-SVQTFRYFAGWCDKIQG-----STIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPL 597

  Fly   197 AVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VVTLCQG-GTDVGQTLV 259
            .:..|.:|..|..||:::.|.|..|||.::.    .||:..:..:|. |:.:..| |..|||.|.
 Frog   598 MMLAWKSAACLAAGNTLVLKPAQVTPLTALK----FAELAVKAGVPKGVINILPGSGGLVGQRLS 658

  Fly   260 ADKRVNLVSFTGSCQTGRDVGVE-VQRRFGKVILELGGNNALII----DESANVKMALDAALFGC 319
            ....:..:.||||...|:.:... ......||.|||||.:.|||    |....|:|.:.|..|
 Frog   659 EHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCDLDKAVRMGMGAVYF-- 721

  Fly   320 IGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGP----VHTQQNVENY 380
              ..|:.|....|:.|.|.:||:||..:|.:.|::  :||..|:..|..||    .|.::.:|..
 Frog   722 --NKGENCIAAGRLFVEESIHDEFVTRVVEEIKKM--RIGDPLDRSTDHGPQNHRAHLEKLLEYC 782

  Fly   381 KAAIAEAKSLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAK--NVDQA 443
            :..:.|    |.|:.:||..:.|.||::||||.|.:.....:...|:|.||:.|.|.|  ::|..
 Frog   783 EIGVKE----GATLVYGGRKVPRPGFFMEPTVFTDVEDHMYLAEEESFGPIMVISKFKDGDIDGV 843

  Fly   444 IEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRESG 508
            :...|..|.||:|.:||::|.:|. ::..| .|.|.|.|| |.|..::...|||.|.:|.|::.|
 Frog   844 LRRANNTEYGLASGVFTKDISKAM-YVSEK-LDAGTVFIN-TYNKTDVAAPFGGFKQSGFGKDLG 905

  Fly   509 SDAWKQYCKRATITVNH 525
            .:|..:|.:...:||.:
 Frog   906 EEALHEYLRTKAVTVEY 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	148/548 (27%)
aldh1l2	XP_002938116.1	FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731
		PP-binding	346..412	CDD:376348	16/67 (24%)
		ALDH_F1L_FTFDH	437..922	CDD:143458	146/507 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000