DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Max and Mnt

DIOPT Version :9

Sequence 1:	NP_001246833.1	Gene:	Max / 40095	FlyBaseID:	FBgn0017578	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_034943.3	Gene:	Mnt / 17428	MGIID:	109150	Length:	591	Species:	Mus musculus

Alignment Length:	138	Identity:	38/138 - (27%)
Similarity:	64/138 - (46%)	Gaps:	18/138 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DIESDEDGDSDTGLGSSRHTNTANFTQAEKRAHHNALERRRRDHIKESFTNLREAVPTLKGEKAS 75
            :.:|.|......|:|:              |..||.||:.||.|:||.|..|:..:|.:..:|.|
Mouse   208 EAKSSEQKKRPGGIGT--------------REVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTS 258

  Fly    76 RAQILKKTTECIQTMRRKISENQKDIEEIKRQNNIIAKQIQALESSNG-DQFSEFLSDEEVGSEE 139
            ...:|:.....||:::||..|.:.::|.:.|:.  ||.|.:..|..:. .|:.:.|..:.|..:.
Mouse   259 NLSVLRTALRYIQSLKRKEKEYEHEMERLAREK--IATQQRLAELKHELSQWMDVLEIDRVLRQT 321

  Fly   140 ADDEDLDQ 147
            ...|| ||
Mouse   322 GQPED-DQ 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Max	NP_001246833.1	HLH	40..91	CDD:278439	18/50 (36%)
Mnt	NP_034943.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	17..122
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	182..223		3/14 (21%)
		HLH	224..274	CDD:278439	18/49 (37%)
		Leucine-zipper	273..301		8/29 (28%)
		DUF2630	281..339	CDD:287859	13/51 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	321..426		4/9 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2483
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810