DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Max and Mxd3

DIOPT Version :9

Sequence 1:	NP_001246833.1	Gene:	Max / 40095	FlyBaseID:	FBgn0017578	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_057871.2	Gene:	Mxd3 / 17121	MGIID:	104987	Length:	206	Species:	Mus musculus

Alignment Length:	136	Identity:	32/136 - (23%)
Similarity:	65/136 - (47%)	Gaps:	17/136 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RAHHNALERRRRDHIKESFTNLREAVPTLKGEKASR---AQILKKTTECIQTMRRKISENQKDIE 102
            |:.||.||:|||..:|.....||:.:|.  |...:|   ..:|::....||.:..:..:.::..|
Mouse    59 RSVHNELEKRRRAQLKRCLEQLRQQMPL--GVDCTRYTTLSLLRRARVHIQKLEEQEQQARRLKE 121

  Fly   103 EIKRQNNIIAKQIQALESSNGDQFSEFLSDEEVGS-------EEADDEDLDQD-----FSRRNKK 155
            :::.:...:.:|::.|:...|.:..|.|..:.:.|       .::|.|||:.|     |....:.
Mouse   122 KLRSKQQSLQQQLEQLQGLPGARERERLRADSLDSSGLSSERSDSDQEDLEVDVESLVFGTETEL 186

  Fly   156 MKTFHA 161
            :::|.|
Mouse   187 LQSFSA 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Max	NP_001246833.1	HLH	40..91	CDD:278439	17/52 (33%)
Mxd3	NP_057871.2	Interaction with SIN3A and SIN3B. /evidence=ECO:0000269\|PubMed:8521822	8..25
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	29..66		3/6 (50%)
		HLH	63..115	CDD:197674	15/53 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	122..171		8/48 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2483
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900