Protein Alignment nes and ALE1

DIOPT Version :9

• Sequence 1: NP_524157.2
• Gene: nes / 40093
• FlyBaseID: FBgn0026630
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_014818.1
• Gene: ALE1 / 854346
• SGDID: S000005701
• Length: 619
• Species: Saccharomyces cerevisiae
• Alignment Length: 515
• Identity: 125/515 - (24%)
• Similarity: 231/515 - (44%)
• Gaps: 77/515 - (14%)

  Fly     9 PHNGLMDGIASGVGVPVEALRLLLTILAGYPVAALYQKFISVIADKTVHHMFFAGCGAGL-CYFN 72
            |.:.::..|.:..|:....||..:.:|..:|:.|:.::    |.:|.:          || |.|.
Yeast     4 PVDAVLTKIITNYGIDSFTLRYAICLLGSFPLNAILKR----IPEKRI----------GLKCCFI 54

  Fly    73 YGLDTYH-----SLIA-----ILTTYFLVLLLRKKTQIFLA-INFVFHMSYLLLGYFYT------ 120
            ..:..::     :|::     .::|.|..|:.|.....|:. :||:|.|.:|.:.:.:.
Yeast    55 ISMSMFYLFGVLNLVSGFRTLFISTMFTYLISRFYRSKFMPHLNFMFVMGHLAINHIHAQFLNEQ 119

  Fly   121 SSNDYDILWTMPHCILVLRMIGYGFDITDG-LKEES---ELSKDQKETALKKPPSLLELLAFSYF 181
            :....||  |....:|.:::..:.:...|| ...||   :|::.||..|::..|.||:.||:::|
Yeast   120 TQTTVDI--TSSQMVLAMKLTSFAWSYYDGSCTSESDFKDLTEHQKSRAVRGHPPLLKFLAYAFF 182

  Fly   182 PSGFLVGPQFPFRRYKAFVD-------------------GEFRQHEGNVEAGVRRFGAGAFYLIV 227
            .|..|.||.|.:..:.::::                   ||.||...|.:..:.:...|..::|:
Yeast   183 YSTLLTGPSFDYADFDSWLNCEMFRDLPESKKPMRRHHPGERRQIPKNGKLALWKVVQGLAWMIL 247

  Fly   228 CQVGLRYLPDSYFLTPE-FAQVSFVKRI---YLLGFWAKFSLYKYISCWLLTEGALICIGLTYKG 288
            ..:|:::.|..|.|..: |...||:.||   :||||..:|   ||.:.|.::||:.|..||.|.|
Yeast   248 STLGMKHFPVKYVLDKDGFPTRSFIFRIHYLFLLGFIHRF---KYYAAWTISEGSCILCGLGYNG 309

  Fly   289 EDKNGQP-DWSGCSNVKLKLLETGNTMEHYVQSFNVNTNQWVGQYIYKRLKFLNNRTISYGAALG 352
            .|...|. .|....|:.:..:||.......::::|:|||:|:...:|.|:.....:.........
Yeast   310 YDSKTQKIRWDRVRNIDIWTVETAQNTREMLEAWNMNTNKWLKYSVYLRVTKKGKKPGFRSTLFT 374

  Fly   353 FL--AVWHGYHSGYYMTFLMEYMVVSTEKQITRFYTKVVLPQWGHI-LNNSDIYKLLYFITLKSY 414
            ||  |.|||...|||:||....:..:..|...|.:..:.|.:.|.. |.:..||.|:....:|
Yeast   375 FLTSAFWHGTRPGYYLTFATGALYQTCGKIYRRNFRPIFLREDGVTPLPSKKIYDLVGIYAIK-- 437

  Fly   415 NVVYMGWCLTAFVFLKYERWIVVYGAVSYY-----GFTFLVLWAAFYHTFNHFFRSSSRK 469
              :..|:.:..|:.|..:..::|:|:|.:|     .|:|.:....:......||:|...|
Yeast   438 --LAFGYMVQPFIILDLKPSLMVWGSVYFYVHIIVAFSFFLFRGPYAKQVTEFFKSKQPK 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nes	NP_524157.2	MBOAT	114..421	CDD:281107	87/343 (25%)
ALE1	NP_014818.1	COG5202	1..563	CDD:227529	125/515 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343107
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54526
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13906
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850