DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nes and LPLAT2

DIOPT Version :9

Sequence 1:	NP_524157.2	Gene:	nes / 40093	FlyBaseID:	FBgn0026630	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_176493.1	Gene:	LPLAT2 / 842608	AraportID:	AT1G63050	Length:	465	Species:	Arabidopsis thaliana

Alignment Length:	466	Identity:	115/466 - (24%)
Similarity:	201/466 - (43%)	Gaps:	67/466 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 MDGIASGVGVPVEALRLLLTILAGYPVAALYQKFISVIADKTVHHMFFAGCGAGLCYFNYGLDT- 77
            |:.:|:.:||.|..||.||..:|..|::.|::    .|..:...|::.|..||.|.|.::|..:
plant     6 MNSMAASIGVSVAVLRFLLCFVATIPISFLWR----FIPSRLGKHIYSAASGAFLSYLSFGFSSN 66

  Fly    78 YHSLIAILTTYFLVLLLRKKTQIFLAINFVFHMSYLLLGYFYTSSNDYDILW-------TMPHCI 135
            .|.|:.:...|..:.:.|..:..   |.|....:||:..:.:..|.|   .|       |....:
plant    67 LHFLVPMTIGYASMAIYRPLSGF---ITFFLGFAYLIGCHVFYMSGD---AWKEGGIDSTGALMV 125

  Fly   136 LVLRMIGYGFDITDGLKEESELSKDQKETALKKPPSLLELLAFSYFPSGFLVGPQFPFRRYKAFV 200
            |.|::|....:..||:.:|..|.:.||:..|.:.|||:|...:.........||.|..:.|.
plant   126 LTLKVISCSINYNDGMLKEEGLREAQKKNRLIQMPSLIEYFGYCLCCGSHFAGPVFEMKDYL--- 187

  Fly   201 DGEFRQHEG---NVEAGVRRFGAGA-----FYLIVCQVGLRYL----PDSYFLTPEFAQVSFVKR 253
              |:.:.:|   ..|.|.|....||     |...:|.....||    |.:.|..|.:.:..|:||
plant   188 --EWTEEKGIWAVSEKGKRPSPYGAMIRAVFQAAICMALYLYLVPQFPLTRFTEPVYQEWGFLKR 250

  Fly   254 I---YLLGFWAKFSLYKYISCWLLTEGALICIGLTYKG--EDKNGQPDWSGCSNVKLKLLETGNT 313
            .   |:.||.|:   :||...|.::|.::|..||.:.|  ::...:..|....||.:..:|...:
plant   251 FGYQYMAGFTAR---WKYYFIWSISEASIIISGLGFSGWTDETQTKAKWDRAKNVDILGVELAKS 312

  Fly   314 MEHYVQSFNVNTNQWVGQYIYKRLKFLNNRTISYGAALGFL---------AVWHGYHSGYYMTFL 369
            .......:|:..:.|:..|:|:|:       :..|...||.         |||||.:.||.:.|:
plant   313 AVQIPLFWNIQVSTWLRHYVYERI-------VKPGKKAGFFQLLATQTVSAVWHGLYPGYIIFFV 370

  Fly   370 MEYMVVSTEKQITRFYTKVVLPQWGHILNNSDIYKLLYFITLKSYNVVYMGWCLTAFVFLKYERW 434
            ...:::...|.|.| :.:.:.|:...:.|   :..|:.|:    |.||.:.:....|:.|.....
plant   371 QSALMIDGSKAIYR-WQQAIPPKMAMLRN---VLVLINFL----YTVVVLNYSSVGFMVLSLHET 427

  Fly   435 IVVYGAVSYYG 445
            :|.:.:|.|.|
plant   428 LVAFKSVYYIG 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nes	NP_524157.2	MBOAT	114..421	CDD:281107	81/339 (24%)
LPLAT2	NP_176493.1	PLN02332	2..465	CDD:215190	115/466 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54526
OrthoDB	1	1.010	-	-		D881262at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13906
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930