DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nes and LPLAT1

DIOPT Version :9

Sequence 1:	NP_524157.2	Gene:	nes / 40093	FlyBaseID:	FBgn0026630	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_172724.2	Gene:	LPLAT1 / 837820	AraportID:	AT1G12640	Length:	462	Species:	Arabidopsis thaliana

Alignment Length:	465	Identity:	115/465 - (24%)
Similarity:	199/465 - (42%)	Gaps:	65/465 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 MDGIASGVGVPVEALRLLLTILAGYPVAALYQKFISVIADKTVHHMFFAGCGAGLCYFNYGLDT- 77
            |..:|..:||.|..||.||..:|..||:...:    ::..:...|::.|..||.|.|.::|..:
plant     3 MSSMAGSIGVSVAVLRFLLCFVATIPVSFACR----IVPSRLGKHLYAAASGAFLSYLSFGFSSN 63

  Fly    78 YHSLIAILTTYFLVLLLRKKTQIFLAINFVFHMSYLLLGYFYTSSNDYDILW-------TMPHCI 135
            .|.|:.:...|..:.:.|.|..|   |.|....:||:..:.:..|.|   .|       |....:
plant    64 LHFLVPMTIGYASMAIYRPKCGI---ITFFLGFAYLIGCHVFYMSGD---AWKEGGIDSTGALMV 122

  Fly   136 LVLRMIGYGFDITDGLKEESELSKDQKETALKKPPSLLELLAFSYFPSGFLVGPQFPFRRYKAFV 200
            |.|::|....:..||:.:|..|.:.||:..|.:.|||:|...:.........||.:..:.|..:.
plant   123 LTLKVISCSMNYNDGMLKEEGLREAQKKNRLIQMPSLIEYFGYCLCCGSHFAGPVYEMKDYLEWT 187

  Fly   201 DG-------EFRQHEGNVEAGVRRFGAGAFYLIVCQVGLRYLPDSYFLT----PEFAQVSFVKRI 254
            :|       |.|:......|.:|.....|    :|.....||...|.||    |.:.:..|:::.
plant   188 EGKGIWDTTEKRKKPSPYGATIRAILQAA----ICMALYLYLVPQYPLTRFTEPVYQEWGFLRKF 248

  Fly   255 ---YLLGFWAKFSLYKYISCWLLTEGALICIGLTYKG--EDKNGQPDWSGCSNVKLKLLETGNTM 314
               |:.||.|:   :||...|.::|.::|..||.:.|  :|.:.:|.|....||.:..:|...:.
plant   249 SYQYMAGFTAR---WKYYFIWSISEASIIISGLGFSGWTDDASPKPKWDRAKNVDILGVELAKSA 310

  Fly   315 EHYVQSFNVNTNQWVGQYIYKRLKFLNNRTISYGAALGFL---------AVWHGYHSGYYMTFLM 370
            ......:|:..:.|:..|:|:||       :..|...||.         |||||.:.||.|.|:.
plant   311 VQIPLVWNIQVSTWLRHYVYERL-------VQNGKKAGFFQLLATQTVSAVWHGLYPGYMMFFVQ 368

  Fly   371 EYMVVSTEKQITRFYTKVVLPQWGHILNNSDIYKLLYFITLKSYNVVYMGWCLTAFVFLKYERWI 435
            ..::::..:.|.| :.:.:.|:...:.|.......||.:.:.:|:.|       .|:.|.....:
plant   369 SALMIAGSRVIYR-WQQAISPKMAMLRNIMVFINFLYTVLVLNYSAV-------GFMVLSLHETL 425

  Fly   436 VVYGAVSYYG 445
            ..||:|.|.|
plant   426 TAYGSVYYIG 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nes	NP_524157.2	MBOAT	114..421	CDD:281107	79/338 (23%)
LPLAT1	NP_172724.2	PLN02332	1..462	CDD:215190	115/465 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54526
OrthoDB	1	1.010	-	-		D881262at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13906
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930