DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nes and mboat4

DIOPT Version :9

Sequence 1:	NP_524157.2	Gene:	nes / 40093	FlyBaseID:	FBgn0026630	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001116416.1	Gene:	mboat4 / 795709	ZFINID:	ZDB-GENE-090421-3	Length:	415	Species:	Danio rerio

Alignment Length:	436	Identity:	98/436 - (22%)
Similarity:	170/436 - (38%)	Gaps:	82/436 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 GYPVAALYQKFISVIADKTVHHMFFAGCGAGLCYFNY-GLDTYHSLIAILTTYFLVLLLRKKTQI 100
            |:|  .|:.:||::......|.:...|..:.:..:.| .:..:...||.:..|..:|.| ...::
Zfish    11 GHP--QLFYQFINIPFAFLFHCLSSQGHLSIINRYVYLAMGGFMLAIATMGPYSSLLFL-SAIKL 72

  Fly   101 FLAINFV--FHMSYLLLG---------YFYTSSNDYDILWTM--PHCILVLRMIGYGFDITDGLK 152
            .|.|:::  .|:...:||         :.|.   .|.|.|..  |...|:|.:..... :|..:
Zfish    73 LLLIHYIHPMHLHRWILGLQMCWQTCWHLYV---QYQIYWLQEAPDSRLLLAISALML-MTQRI- 132

  Fly   153 EESELSKDQKETALKKPPSLLELLAFS-YFPSGFLVGPQFPFRRYKAFVDGEFRQHE------GN 210
              |.||.|.:|..:.....|:..|.:| |||:  |:|.  |...:.|||....|||.      ||
Zfish   133 --SSLSLDFQEGTISNQSILIPFLTYSLYFPA--LLGG--PLCSFNAFVQSVERQHTSMTSYLGN 191

  Fly   211 VEAGVRRFGAGAFYLIVCQVGLRYLPDSYFLTPEFAQVSFVKRIYLLGFWAKFSL---YKYISCW 272
            :.:.:.:        ::..|.::.|......:..|...|..  :.:|..|. |||   ..|.:.|
Zfish   192 LTSKISQ--------VIVLVWIKQLFSELLKSATFNIDSVC--LDVLWIWI-FSLTLRLNYYAHW 245

  Fly   273 LLTEGALICIGLTYKGEDKNGQPDWSGCSNVKLKLLETGNTMEHYVQSFNVNTNQWVGQYIYKRL 337
            .::|......||.......:||..|...|:..:.:.|..:....:.:.:|..|..|:.:.::.|
Zfish   246 KMSECVNNAAGLGVYFHKHSGQTSWDELSDGSVLVTEASSRPSVFARKWNQTTVDWLRKIVFNR- 309

  Fly   338 KFLNNRTISYGAALGFLAVWHGYHSGYYMTFLMEYMVVSTEKQITRFYTKVVLPQWGHILNNSDI 402
               .:|:..: ...||.|:|||.|.|..:.||:..:.|..:.::.||         .|...||..
Zfish   310 ---TSRSPLF-MTFGFSALWHGLHPGQILGFLIWAVTVQADYKLHRF---------SHPKLNSLW 361

  Fly   403 YKLLYF-----------------ITLKSYNVVYMGW--CLTAFVFL 429
            .|.||.                 :.|:|...|.:.|  |:..|..|
Zfish   362 RKRLYVCVNWAFTQLTVACVVVCVELQSLASVKLLWSSCIAVFPLL 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nes	NP_524157.2	MBOAT	114..421	CDD:281107	78/344 (23%)
mboat4	NP_001116416.1	MBOAT	19..399	CDD:294479	92/416 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D881262at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820