DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nes and Mboat7

DIOPT Version :9

Sequence 1:	NP_524157.2	Gene:	nes / 40093	FlyBaseID:	FBgn0026630	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_084210.2	Gene:	Mboat7 / 77582	MGIID:	1924832	Length:	473	Species:	Mus musculus

Alignment Length:	473	Identity:	110/473 - (23%)
Similarity:	190/473 - (40%)	Gaps:	90/473 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LLTILAGYPVAALYQKFISVIADKTVHHMFFAGCGAGLCYFNYGLDTYHSLIAILTTYFLVLLLR 95
            |:.:|...||..|::|     |...:.....|..|.||..|..|..:.||||.||.|:.|:....
Mouse     9 LMVLLISIPVGFLFKK-----AGPGLKRWGAAAVGLGLTLFTCGPHSLHSLITILGTWALIQAQP 68

  Fly    96 KKTQIFLAINFVFHMSYLLLGYFYTSSNDYDILWTMP---------HCILVLRMIGYGFDITD-G 150
            ..... ||:.:.|  ||||  :|...|     |..:|         ..:|.|:::....::.| .
Mouse    69 CSCHA-LALAWTF--SYLL--FFRALS-----LLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLH 123

  Fly   151 LKEESELS----KDQKETALKKPPSLLELLAFSYFPSGFLVGPQFPFRRYKAFVDGEFRQHEGNV 211
            |.:..|::    |:.....|.:.|||:|.|::||...|.:.||.|.:|.|..:::..|.:...::
Mouse   124 LAQRKEIASGFHKEPTLGLLPEVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPEAVPSL 188

  Fly   212 EAGVRRFGAGAFYLIVCQVGLRYLPDSYFLTPE-------FAQVSFVKRIYLLGFWAKFSLYKYI 269
            ...:||......:      ||.:|..|:....|       :|:....:..|::..:..|.:..|:
Mouse   189 RPLLRRAWPAPLF------GLLFLLSSHLFPLEAVREDAFYARPLPTRLFYMIPVFFAFRMRFYV 247

  Fly   270 SCWLLTEGALICIGL-TYKGEDK---NGQP------------------DWSGCSNVKLKLLETGN 312
            : |:..|...|..|. .|....|   .|.|                  |:....|:.....:...
Mouse   248 A-WIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEIAASLEYDYETIRNIDCYGTDFCV 311

  Fly   313 TMEHYVQSFNVNTNQWVGQYIYKRLKFLNNRTISYGAALGFL--AVWHGYHSGYYMTFLMEYMVV 375
            .:...::.:|:....|:.|||||...|   |:....:|...|  |.|||.|.|||::|:...:.:
Mouse   312 RVRDGMRYWNMTVQWWLAQYIYKSAPF---RSYVLRSAWTMLLSAYWHGLHPGYYLSFMTIPLCL 373

  Fly   376 STEKQITRFYTKVVLP------QWGHILNNSDIYKLLYFITLKSYNVVYMGWCLTAFV-FLKYER 433
            :.|..:.....:.:.|      .|.|           :|:.:::|:.:.||:.|.:.. .|:|
Mouse   374 AAEGYLESALRRHLSPGGQKAWDWVH-----------WFLKMRAYDYMCMGFVLLSMADTLRY-- 425

  Fly   434 WIVVYGAVSYYGFTFLVL 451
            |..:|..|.:.....|.|
Mouse   426 WASIYFWVHFLALACLGL 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nes	NP_524157.2	MBOAT	114..421	CDD:281107	74/357 (21%)
Mboat7	NP_084210.2	MBOAT	8..431	CDD:382173	106/459 (23%)
Mboat7	NP_084210.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	451..473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D881262at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820