DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nes and SPBC16A3.10

DIOPT Version :9

Sequence 1:	NP_524157.2	Gene:	nes / 40093	FlyBaseID:	FBgn0026630	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_596779.1	Gene:	SPBC16A3.10 / 2539940	PomBaseID:	SPBC16A3.10	Length:	509	Species:	Schizosaccharomyces pombe

Alignment Length:	542	Identity:	134/542 - (24%)
Similarity:	238/542 - (43%)	Gaps:	90/542 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DLPHNGLMDGIASGVGVPVEALRLLLTILAGYPVAALYQKFISVIADKTVHHMFFAGCGAGLCYF 71
            |:|    .:..:|.:||..:.|:||...|:.||.|.:.::..|.   ..:.::|  ....||.|.
pombe     6 DIP----FEYFSSFLGVHPDQLKLLFCFLSAYPFAGILKRLPSA---PWIRNLF--SISIGLFYL 61

  Fly    72 NYGLDTYH-------SLIAILTTYFLVLLLRKKTQ---IFLAI---NFVFHMSYLLLGYFYTSSN 123
               :..:|       .|...|.|||:....|....   ||:.|   .|..|    ::.|.|.|.|
pombe    62 ---IGVHHLYDGVLVLLFDALFTYFVAAFYRSSRMPWIIFIVILGHTFSSH----VIRYIYPSEN 119

  Fly   124 DYDILWTMPHCILVLRMIGYGFDITDGLKEESELSKDQKETALKKPPSLLELLAFSYFPSGFLVG 188
            . ||  |....:|.:::..:.:.:.||....||||..||:.||:|.|::|..|.:.:|....|||
pombe   120 T-DI--TASQMVLCMKLTAFAWSVYDGRLPSSELSSYQKDRALRKIPNILYFLGYVFFFPSLLVG 181

  Fly   189 PQFPFRRYKAFV------------DGEFRQHEGNVEAGVRRFGAGAFYLIVCQVGLRYLPDSYFL 241
            |.|.:..|:.|:            :.:...|  ::|..:.|...|..:||:...|....|..:.|
pombe   182 PAFDYVDYERFITLSMFKPLADPYEKQITPH--SLEPALGRCWRGLLWLILFITGSSIYPLKFLL 244

  Fly   242 TPEFAQVSFVKRIYLLGFWAKFSLYKYISCWLLTEGALICIGLTYKGEDKNGQPDWSGCSNVKLK 306
            ||:||....:.:...:...|..:..||...|.|::||.|..|:.|.|.|.:..|.|....|:...
pombe   245 TPKFASSPILLKYGYVCITAFVARMKYYGAWELSDGACILSGIGYNGLDSSKHPRWDRVKNIDPI 309

  Fly   307 LLETGNTMEHYVQSFNVNTNQWVGQYIYKRL----------KFLNNRTISYGAALGFLAVWHGYH 361
            ..|..:.::..::::|:|||:|:..|:|.|:          ..|:..|:|        |:|||..
pombe   310 KFEFADNIKCALEAWNMNTNKWLRNYVYLRVAKKGKRPGFKSTLSTFTVS--------AMWHGVS 366

  Fly   362 SGYYMTFL----MEYMVVSTEKQITRFYTKVVLPQWGHILNNSDIYKLLYFITLKSYNVVYMGWC 422
            :|||:||:    ::.:...|.:.:..|:.|..:...|.       :|.:|.:.......:.:.:.
pombe   367 AGYYLTFVSAAFIQTVAKYTRRHVRPFFLKPDMETPGP-------FKRVYDVIGMVATNLSLSYL 424

  Fly   423 LTAFVFLKYERWIVVYGAVSYYGFTFLVLWAAFYHTFNHFFRS----------SSRKLAGEDQKL 477
            :.:|:.|..:..|.|:..:.:....::::..|   .||...||          :|.||...:|.:
pombe   425 IISFLLLNLKESIHVWKELYFIVHIYILIALA---VFNSPIRSKLDNKIRSRVNSYKLKSYEQSM 486

  Fly   478 QD-SNTDKL-VEEKKPEDKKSE 497
            :. |:||.| :...|.||.:::
pombe   487 KSTSDTDMLNMSVPKREDFEND 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nes	NP_524157.2	MBOAT	114..421	CDD:281107	85/332 (26%)
SPBC16A3.10	NP_596779.1	COG5202	1..509	CDD:227529	134/542 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54526
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13906
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920