DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nes and Mboat1

DIOPT Version :9

Sequence 1:	NP_524157.2	Gene:	nes / 40093	FlyBaseID:	FBgn0026630	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_705774.1	Gene:	Mboat1 / 218121	MGIID:	2387184	Length:	492	Species:	Mus musculus

Alignment Length:	457	Identity:	101/457 - (22%)
Similarity:	192/457 - (42%)	Gaps:	57/457 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 VGVPVEALRLLLTILAGYPVAALYQKFISV-IADKTVHHMFFAGCGAGLCYFNYGLDTYHSLIAI 84
            :|:|::.:..:...|.....|..::.::.. .|...|.|......|.....|.:|....|..:.:
Mouse    26 LGIPLDQVNFVACQLFALSAAFWFRIYLHPGKASPEVRHTLATILGIYFVVFCFGWYAVHLFVLV 90

  Fly    85 LTTYFLVLLLR----KKTQIFLAINF--VFHMSYLLLGYFYTSSNDYDILWTMPHCILVLRMIGY 143
            |..|.:::...    .:...|:|:.:  :.|:|.:.:.::...:.|:    :.|..|:..::...
Mouse    91 LMCYGVMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDF----SGPLMIVTQKITTL 151

  Fly   144 GFDITDGLKEESE-LSKDQKETALKKPPSLLELLAFSYFPSGFLVGPQFPFRRYKAFVDGEFRQH 207
            .|.:.|||..::| ||.:|...|:|..|||||.|::.......:.||...|:.|.||::|. ..|
Mouse   152 AFQVHDGLGRKAEDLSAEQHRLAVKAKPSLLEYLSYHLNFMSVIAGPCNNFKDYVAFIEGR-HIH 215

  Fly   208 EGNVEAGVRRFG---------AGAFYLIVC--------------QVGLRYLPDSYFLTPEFAQVS 249
            ...:|....:.|         .||....:|              ...:.:|.|.:|:    .:.:
Mouse   216 MKLLEVNWTQRGFQSLPEPSPMGAVIQKLCVTLMSLLLFLTLSKSFPVTFLIDDWFV----HKAN 276

  Fly   250 FVKRIYLLGFWAKFSLYKYISCWLLTEGALICIGLTYKGEDKNGQPDWSGCSNVKLKLLETGNTM 314
            |:.|::.|....:.:..||...|.|.:......|..:.|.|.:|:..|...||:.:..:||..:.
Mouse   277 FLSRLWYLYVVMQAAKPKYYFAWTLADAVHNAAGFGFNGMDTDGKSRWDLLSNLNIWKIETATSF 341

  Fly   315 EHYVQSFNVNTNQWVGQYIYKRLKFLNNRTISYGAALGFL--AVWHGYHSGYYMTFLMEYMVVST 377
            :.|::::|:.|:.|:....|:|:.:       |...|.||  |:|||.:.|||.|||....|...
Mouse   342 KMYLENWNIQTSTWLKCVCYERVPW-------YPTVLTFLLSALWHGVYPGYYFTFLTGVPVTLA 399

  Fly   378 EKQITRFYTKVVLPQWGHILNNSDIYKLLYFITLKSYNVVYMGWCLTAFVFLKYERWIVVYGAVS 442
            .:.:...|.        |...:|...|:.|.:...:...:.:.:....||.|..|..|.:|.:|.
Mouse   400 ARAVRNNYR--------HHFLSSKARKIAYDVVTWAVTQLAVSYTAAPFVMLAVEPTISLYKSVF 456

  Fly   443 YY 444
            ::
Mouse   457 FF 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nes	NP_524157.2	MBOAT	114..421	CDD:281107	77/332 (23%)
Mboat1	NP_705774.1	MBOAT	21..458	CDD:294479	101/455 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54526
OrthoDB	1	1.010	-	-		D881262at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830