Protein Alignment nes and MBOAT2

DIOPT Version :10

• Sequence 1: NP_524157.2
• Gene: nes / 40093
• FlyBaseID: FBgn0026630
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_620154.2
• Gene: MBOAT2 / 129642
• HGNCID: 25193
• Length: 520
• Species: Homo sapiens
• Alignment Length: 525
• Identity: 114/525 - (21%)
• Similarity: 221/525 - (42%)
• Gaps: 109/525 - (20%)

  Fly    13 LMDGIASGVGVPVEALRLLLTILAGYPVAALYQKFISVIADKT---VHHMFFAGCGAGLCYFNYG 74
            |:..:::.|.:|::.:..::..|.....|..::.::.  :.||   :.|:.....|..|..|.:|
Human    11 LLQPLSNAVQLPIDQVNFVVCQLFALLAAIWFRTYLH--SSKTSSFIRHVVATLLGLYLALFCFG 73

  Fly    75 LDTYHSLIAILTTYFLVLLLRKKTQIFLAINFVFHMSYL----LLGYFYTSSNDYDILWTMPHCI 135
            ....|.|:....:|.:::::..:......  |||.:.||    :...:......|...::.|..|
Human    74 WYALHFLVQSGISYCIMIIIGVENMHNYC--FVFALGYLTVCQVTRVYIFDYGQYSADFSGPMMI 136

  Fly   136 LVLRMIGYGFDITDGL-KEESELSKDQKETALKKPPSLLELLAFSYFPSGFLVGPQFPFRRYKAF 199
            :..::.....:|.||: :::.||:..|::.|:::.|||||.|:::....|.|.||...::.|..|
Human   137 ITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITF 201

  Fly   200 VDG----------------EFRQHEGNVEAGVRRFGAGAFYLIVCQVGLRY-------LPDSYFL 241
            ::|                ::.:.|.:....|.:      .|:||.:.|.:       ||..|.:
Human   202 IEGRSYHITQSGENGKEETQYERTEPSPNTAVVQ------KLLVCGLSLLFHLTICTTLPVEYNI 260

  Fly   242 TPEF-AQVSFVKRIYLLGFWAKFSLYKYISCWLLTEGALICIGLTYKGEDKNGQPDWSGCSNVKL 305
            ...| |..|:..:|..|......:..||...|.|.:......|..::|.|:||...|...||:::
Human   261 DEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRI 325

  Fly   306 KLLETGNTMEHYVQSFNVNTNQWVGQYIYKRLKFLNNRTISYGAALGFL--AVWHGYHSGYYMTF 368
            :.:|...:.:.::.::|:.|..|:.:..|:|..|  :.||.     .|:  |:|||.:.|||:||
Human   326 QQIEMSTSFKMFLDNWNIQTALWLKRVCYERTSF--SPTIQ-----TFILSAIWHGVYPGYYLTF 383

  Fly   369 LMEYMVVSTEKQITRFYTKVVLPQWGHILNNSDIYKLLYFI---TLK-SYNVVYMGWCLTAFVFL 429
            |                |.|::......:.|:..:   |||   .|| .|:|:
Human   384 L----------------TGVLMTLAARAMRNNFRH---YFIEPSQLKLFYDVI------------ 417

  Fly   430 KYERWIVVYGAVSYYGFTFLVL--------WAAFYHTFNHFF-----------RSSSRKLAGEDQ 475
               .|||...|:||....|::|        ::::|:.. |..           ::..||...|:.
Human   418 ---TWIVTQVAISYTVVPFVLLSIKPSLTFYSSWYYCL-HILGILVLLLLPVKKTQRRKNTHENI 478

  Fly   476 KLQDS 480
            :|..|
Human   479 QLSQS 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nes	NP_524157.2	MBOAT	114..421	CDD:427117	79/337 (23%)
MBOAT2	NP_620154.2	MBOAT	13..450	CDD:445070	106/487 (22%)