Protein Alignment CHCHD10 and Chchd2

DIOPT Version :9

• Sequence 1: NP_001288268.1
• Gene: CHCHD10 / 400916
• HGNCID: 15559
• Length: 149
• Species: Homo sapiens
• Sequence 2: NP_573196.1
• Gene: Chchd2 / 32701
• FlyBaseID: FBgn0260747
• Length: 170
• Species: Drosophila melanogaster
• Alignment Length: 175
• Identity: 77/175 - (44%)
• Similarity: 95/175 - (54%)
• Gaps: 36/175 - (20%)

Human     1 MPRGSRSAASRPASRPAAP-SAHPPA---------HPPPSAAAPAPAPSG------------QPG 43
            |.|..|||:..|::|..|| .|..||         .|.|:|:||.|||..            ||.
  Fly     1 MVRRGRSASPPPSTRRTAPVQARAPAPAPAPVQTRAPAPAASAPVPAPMSAPPSAVGMPAPQQPS 65

Human    44 LMAQMATTAAGVAVGSAVGHVMGSALTGAFSG-GSSE-------PSQPAVQQPLALYPQAPTPAA 100
            :..|||.||.|||||||:||.:|..||..||| |..|       .:.||.|||  .|.|...|..
  Fly    66 MFQQMAATAGGVAVGSAIGHTVGHGLTSLFSGSGDKEAAAPAPAAAAPAPQQP--YYAQQQQPNE 128

Human   101 PQPLQMGPCAYEIRQFLDCSTTQSDLSLCEGFSEALKQCKYYHGL 145
            ||    |.||:|::||:.|:..|:||:|||||:|||:|||..|.|
  Fly   129 PQ----GACAWELKQFIQCAQGQADLTLCEGFNEALRQCKQSHHL 169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHCHD10	NP_001288268.1	DUF2076	<40..>88	CDD:331414	27/67 (40%)
		CHCH	109..140	CDD:310983	18/30 (60%)
Chchd2	NP_573196.1	CHCH	133..165	CDD:284221	19/31 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4090
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4528
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54220
OrthoDB	1	1.010	-	-		D1611117at2759
OrthoFinder	1	1.000	-	-		FOG0001898
OrthoInspector	1	1.000	-	-		otm41009
orthoMCL	1	0.900	-	-		OOG6_103181
Panther	1	1.100	-	-	LDO	PTHR13523
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2188
SonicParanoid	1	1.000	-	-		X1616
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.870