DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL21 and MRPL21

DIOPT Version :9

Sequence 1:	NP_001262039.1	Gene:	mRpL21 / 40091	FlyBaseID:	FBgn0036853	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	XP_005273880.1	Gene:	MRPL21 / 219927	HGNCID:	14479	Length:	280	Species:	Homo sapiens

Alignment Length:	183	Identity:	55/183 - (30%)
Similarity:	92/183 - (50%)	Gaps:	24/183 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FLAQTMRQMLRHVPNRSLLTAGAMRPLSISPVIGQQNKPATESVDLSAIAKDQQKECLSICERIN 67
            |.:|:...:..:||..||.:......:...||                   ::.:....:.:::|
Human    39 FNSQSTSYLPGYVPKTSLSSPPWPEVVLPDPV-------------------EETRHHAEVVKKVN 84

  Fly    68 RQVQKSEQGRLFAVVHLCGKQFKVTPGDIILVEGYWPPTIGDEISLDKVLLAGARDFTLVGRPIL 132
            ..:...:.||||||||...:|:|||..|:||:........|:.|.|:||||.||.:|||:|:|:|
Human    85 EMIVTGQYGRLFAVVHFASRQWKVTSEDLILIGNELDLACGERIRLEKVLLVGADNFTLLGKPLL 149

  Fly   133 EPGLILVKATVVEKTLSHTKTHFRKKRRKQYMRINFQRSPHTMVRINSIELAR 185
            ...|:.|:|||:|||.|..:...|.::||     ||::....:.::....:||
Human   150 GKDLVRVEATVIEKTESWPRIIMRFRKRK-----NFKKKRSKLEKVPLGPVAR 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL21	NP_001262039.1	Ribosomal_L21p	85..175	CDD:279202	36/89 (40%)
MRPL21	XP_005273880.1	Ribosomal_L21p	102..179	CDD:279202	34/81 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147341
Domainoid	1	1.000	89	1.000	Domainoid score	I7898
eggNOG	1	0.900	-	-		E1_COG0261
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32936
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4953
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004347
OrthoInspector	1	1.000	-	-		oto91660
orthoMCL	1	0.900	-	-		OOG6_101040
Panther	1	1.100	-	-	LDO	PTHR21349
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5441
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.750