DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz2 and sfrp2

DIOPT Version :9

Sequence 1:	NP_001262037.1	Gene:	fz2 / 40090	FlyBaseID:	FBgn0016797	Length:	806	Species:	Drosophila melanogaster
Sequence 2:	NP_001070852.2	Gene:	sfrp2 / 566878	ZFINID:	ZDB-GENE-061013-293	Length:	294	Species:	Danio rerio

Alignment Length:	138	Identity:	52/138 - (37%)
Similarity:	75/138 - (54%)	Gaps:	7/138 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 HGLDASPAPGYGVPVIPKDPNLRCEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLV 105
            |||.|...|    .:..|..|.:.....:.:|..|.|.....||.:.|||.:|...:...:.|||
Zfish    21 HGLYAFDQP----ELFQKKSNCKPIPTNLLLCHDIEYTNMRLPNLLGHETMNEVLQQASSWTPLV 81

  Fly   106 EIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLH 170
            :.:|.||.|.||||::.|:||:|..:|:..|||:||..:|||||:|..:.|.||:.:.|...||.
Zfish    82 QKQCHPDTKKFLCSLFAPVCLDDLDEPIQPCRSLCESVKSGCAPVMAAFGFPWPDMLDCRRFPLD 146

  Fly   171 GDPDNLCM 178
            .|   ||:
Zfish   147 ND---LCI 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz2	NP_001262037.1	CRD_FZ5_like	63..182	CDD:143565	45/116 (39%)
fz2	NP_001262037.1	Frizzled	308..618	CDD:279827
sfrp2	NP_001070852.2	CRD_SFRP2	34..161	CDD:143555	47/121 (39%)
sfrp2	NP_001070852.2	NTR_Sfrp1_like	167..294	CDD:239635
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810