Protein Alignment fz2 and fz

DIOPT Version :9

• Sequence 1: NP_001262037.1
• Gene: fz2 / 40090
• FlyBaseID: FBgn0016797
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_001261836.1
• Gene: fz / 45307
• FlyBaseID: FBgn0001085
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 692
• Identity: 250/692 - (36%)
• Similarity: 353/692 - (51%)
• Gaps: 146/692 - (21%)

  Fly     6 LKVLILGLVLLLTSCRAD-GPLHSADH---GMGGMGMGGHGLDASPAPGYGVPVIPKDPNLRCEE 66
            |..||.|:.      |.| .||.::.:   |.|.|...|..||..|            .:.|||.
  Fly     9 LPTLIQGVQ------RYDQSPLDASPYYRSGGGLMASSGTELDGLP------------HHNRCEP 55

  Fly    67 ITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPIC--LEDY 129
            |||.:|:.|.||||..||.:.|..|:|||||||||.|||:|.||.||:.||||:|.|:|  ||
  Fly    56 ITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILE-- 118

  Fly   130 HKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGG 194
             :|:|.|||:||.||. |..:|:.|:|.|||.:.|...|:||..| ||:.:.:
  Fly   119 -RPIPPCRSLCESARV-CEKLMKTYNFNWPENLECSKFPVHGGED-LCVAENT------------ 168

  Fly   195 SGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRG-------RNSKNCQNPQGEKASGKE 252
                                       .||.||:..|.|.       ::....::|  .:..|..
  Fly   169 ---------------------------TSSASTAATPTRSVAKVTTRKHQTGVESP--HRNIGFV 204

  Fly   253 CSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAG--VPNCGIPCKGPFFSNDEKD 315
            |....::|| .:|.|                        .::.|  :.:||.||...||...|:.
  Fly   205 CPVQLKTPL-GMGYE------------------------LKVGGKDLHDCGAPCHAMFFPERERT 244

  Fly   316 FAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIAC 380
            ....|:..|:.:|..|.|.|:.||:||:.||:||||.||||:.||.:|...|:: .....:.::|
  Fly   245 VLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVA-GLGAGDSVSC 308

  Fly   381 ----------DGLLLRESSTGPH----SCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNE 431
                      ..|.:..:.|..|    |||::|:..||..||:..||..|:|.||||||||||:|
  Fly   309 REPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHE 373

  Fly   432 AITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGT 496
            ||...|..|||.||.:|.:|:::||.|:.|:||.:.|:|:||.|:...|..|::.||.:||.||.
  Fly   374 AIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGA 438

  Fly   497 TFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFE 561
            .||:|||:||||||:|:|..     |.:.||||:||:|||.||.|:.:||..::||..||...|:
  Fly   439 LFLLAGFISLFRIRTVMKTD-----GKRTDKLERLMLRIGFFSGLFILPAVGLLGCLFYEYYNFD 498

  Fly   562 DWI--------KALACPCAQVKGPGK---KPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRR 615
            :|:        |..:.||...:.||.   :|::.:.|:||..::.||:||.||::|.||:.|||.
  Fly   499 EWMIQWHRDICKPFSIPCPAARAPGSPEARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWRN 563

  Fly   616 FWRRLLGAPDRTGANQALI----------KQRPPIPHPYAGS 647
            |..||.|...||.| ||.:          |..|..|.|.|.:
  Fly   564 FVERLQGKEPRTRA-QAYVXYETGPAGGAKSTPLTPDPEAAN 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fz2	NP_001262037.1	CRD_FZ5_like	63..182	CDD:143565	65/120 (54%)
		Frizzled	308..618	CDD:279827	139/334 (42%)
fz	NP_001261836.1	CRD_FZ1_like	51..167	CDD:143567	65/120 (54%)
		Frizzled	237..564	CDD:279827	138/332 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438645
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D24176at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11309
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X126
	6	5.850