Protein Alignment fz2 and Fzd10

DIOPT Version :9

• Sequence 1: NP_001262037.1
• Gene: fz2 / 40090
• FlyBaseID: FBgn0016797
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_001258121.1
• Gene: Fzd10 / 363913
• RGDID: 1583825
• Length: 582
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 274/679 - (40%)
• Similarity: 349/679 - (51%)
• Gaps: 163/679 - (24%)

  Fly     9 LILGLVLLLTSCRADGPLHSADHGMGGMGMGGHGLDASPAPGYGVPVIPKDPNLRCEEITIPMCR 73
            |.|.|.:::.||.|   :.|.|               ...||.|          :|:.:.||||:
  Rat     8 LWLMLQVMMGSCAA---ISSMD---------------LERPGDG----------KCQPVEIPMCK 44

  Fly    74 GIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRS 138
            .||||.|..||.|.||.|.||.:::|:|.||||..|...|:|||||:|.|:|.|....|:|.||.
  Rat    45 DIGYNTTRMPNLMGHENQREAAIQLHEFAPLVEYGCHGHLRFFLCSLYAPMCTEQVSTPIPACRV 109

  Fly   139 VCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSG---- 199
            :||:||..|:|||:|:.|.||:.:.|..||...||:.||||.|      :.||...|.|||
  Rat   110 MCEQARLKCSPIMEQFKFRWPDSLDCSKLPNKNDPNYLCMEAP------NNGSDEPSRGSGMFPP 168

  Fly   200 ------SGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGEKASGK----ECS 254
                  ..|......|.||.|..|                      |.||      ||    |.|
  Rat   169 LFRPQRPHSAQEHPLKDGGPGRAG----------------------CDNP------GKFHHVEKS 205

  Fly   255 CSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGL 319
            .||                                       .|.| .|....::|.|:|.||.:
  Rat   206 ESC---------------------------------------APLC-TPGVDVYWSRDDKRFAVV 230

  Fly   320 WIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLL 384
            |:|:||.|||.|:..|:.||:||..||:||||||:|||.||.:.:|||:.|.|...|.||||
  Rat   231 WLAIWSVLCFFSSAFTVLTFLIDPSRFRYPERPIIFLSMCYCVYSVGYIIRLFAGAESIACD--- 292

  Fly   385 LRES-----------STGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQ 438
             |:|           |||   ||||||:.|:||||||:|||:|:.|||||||.|||:|||..:|.
  Rat   293 -RDSGQLYVIQEGLESTG---CTLVFLVLYYFGMASSLWWVVLTLTWFLAAGRKWGHEAIEANSS 353

  Fly   439 YFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGF 503
            |||||||.||.|:::.:|::..|.||.:.|:||||:::.:.|..|||.||..||||||:|:::||
  Rat   354 YFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLVPLACYLVIGTSFILSGF 418

  Fly   504 VSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALA 568
            |:||.||.|:|.     .|...|||||||:|||:||:|||||||.||.||.||....:.| |.||
  Rat   419 VALFHIRRVMKT-----GGENTDKLEKLMVRIGVFSLLYTVPATCVIACYFYERLNMDYW-KMLA 477

  Fly   569 -------------CPCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRL 620
                         ..|....   ..|...|.|:|..|.|.||||||||:|:.|||:||::...|.
  Rat   478 TQHKCKTNNQTKTADCLMTT---SIPAVEVFMVKVSMLLVVGITSGVWVWTSKTLQSWQQVCSRG 539

  Fly   621 LGAPDR-------TGANQALIKQRPPIPH 642
            |....|       |.|......|.|..||
  Rat   540 LKRKSRRKPASVVTSAGIYKKAQHPQKPH 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fz2	NP_001262037.1	CRD_FZ5_like	63..182	CDD:143565	60/118 (51%)
		Frizzled	308..618	CDD:279827	169/333 (51%)
Fzd10	NP_001258121.1	CRD_FZ	31..157	CDD:295308	64/141 (45%)
		Frizzled	219..536	CDD:279827	169/332 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D237456at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010