Protein Alignment fz2 and fzd7b

DIOPT Version :9

• Sequence 1: NP_001262037.1
• Gene: fz2 / 40090
• FlyBaseID: FBgn0016797
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_739569.1
• Gene: fzd7b / 30412
• ZFINID: ZDB-GENE-990415-229
• Length: 557
• Species: Danio rerio
• Alignment Length: 643
• Identity: 277/643 - (43%)
• Similarity: 353/643 - (54%)
• Gaps: 153/643 - (23%)

  Fly    26 LHSAD-HGMGGMGMGGHGLDASPAPGYGVPVIPKDPNLRCEEITIPMCRGIGYNMTSFPNEMNHE 89
            |.||. ||..|:.:..||.                    |:.|:||:|..|.||.|..||.:.|.
Zfish    26 LSSAQYHGEKGISVPEHGF--------------------CQPISIPLCTDIQYNQTIMPNLLGHT 70

  Fly    90 TQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPIC--LEDYHKPLPVCRSVCERARSGCAPIMQ 152
            .|::||||||||:|||:::||.||||||||||.|:|  ||   :.:|.||::|||||.||..:|.
Zfish    71 NQEDAGLEVHQFYPLVKVQCSQDLKFFLCSMYAPVCTVLE---QAIPPCRTLCERARQGCEALMN 132

  Fly   153 QYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGG 217
            ::.|:||||:.||:.|:|
Zfish   133 KFGFQWPERLRCENFPVH----------------------------------------------- 150

  Fly   218 SGAGGSSGSTSTKPCRGRNSKN----CQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPM 278
             |||        :.|.|:|..:    ..||               :|.|         .:...|.
Zfish   151 -GAG--------EICVGQNKSDPDVPTTNP---------------TPYI---------PEPFSPR 182

  Fly   279 MHHPHH-----WYMNLTV-----QRIAGVPNCGIPC--KGP----FFSNDEKDFAGLWIALWSGL 327
            :|.|..     ..:.|||     ....|..|||.||  |.|    :|..:|..|..||:.:||.|
Zfish   183 IHTPRQNQAFTCPLQLTVPSYLNYHFLGAKNCGAPCEHKQPYGLMYFKEEEVRFGRLWVGIWSIL 247

  Fly   328 CFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIAC------DGLLLR 386
            |..|||.|:.|:::|..||.||||||:|||.|||||||.| :..||..:::.|      |.....
Zfish   248 CCVSTLFTVLTYLVDMRRFHYPERPIIFLSGCYFMVAVAY-AAGFLLEDKVVCIDKFRDDAFKTV 311

  Fly   387 ESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQ 451
            ...|....||::|::.|||||||||||||||.||||:||:|||:|||..:|||||||||.:|.|:
Zfish   312 AQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAVK 376

  Fly   452 SVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQ 516
            ::.:|.|..||||.:.|:||||..|.|.|:.||||||||||.|||:||:||||||||||:::|..
Zfish   377 TITILALGQVDGDLLTGVCYVGIYNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHD 441

  Fly   517 GGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDW--------IKALACPCAQ 573
                 |.|.:||||||:|||:|||||||||||||.||.||.|:.|.|        .|..|.||..
Zfish   442 -----GTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFREQWEKTWHMQTCKRFAVPCPN 501

  Fly   574 VKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGAPDRTGANQ 631
            .......|.::|.|:||.|.:.||||||.||||||||:|||||::||       |.||
Zfish   502 NNFAPMTPDFTVFMIKYLMTMIVGITSGFWIWSGKTLQSWRRFYKRL-------GNNQ 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fz2	NP_001262037.1	CRD_FZ5_like	63..182	CDD:143565	60/120 (50%)
		Frizzled	308..618	CDD:279827	180/323 (56%)
fzd7b	NP_739569.1	CRD_FZ1_like	43..161	CDD:143567	66/196 (34%)
		Frizzled	228..545	CDD:279827	179/322 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X126
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810