Protein Alignment fz2 and smo

DIOPT Version :9

• Sequence 1: NP_001262037.1
• Gene: fz2 / 40090
• FlyBaseID: FBgn0016797
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_571102.2
• Gene: smo / 30225
• ZFINID: ZDB-GENE-980526-89
• Length: 822
• Species: Danio rerio
• Alignment Length: 601
• Identity: 157/601 - (26%)
• Similarity: 255/601 - (42%)
• Gaps: 151/601 - (25%)

  Fly    64 CEEITIPMCRG--IGYNMTSFPNEMNHETQDEAGLEVHQFW------PLVEIKCSPDLKFFLCSM 120
            ||.:....|.|  :.|..||.....:.|||:|| .|....|      |    :|...::..||::
Zfish    48 CEVLKYNTCLGSPLPYTHTSLILAEDSETQEEA-FEKLAMWSGLRNAP----RCWAVIQPLLCAV 107

  Fly   121 YTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTE 185
            |.|.| |:....|| .:.:|:..|:.|:.:.::..  ||..:.||:
Zfish   108 YMPKC-ENGKVELP-SQHLCQATRNPCSIVERERG--WPNFLKCEN------------------- 149

  Fly   186 AGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGE---K 247
                                                           :.:..|.|||...:   .
Zfish   150 -----------------------------------------------KEQFPKGCQNEVQKLKFN 167

  Fly   248 ASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSND 312
            .||:     |.:||:   |..:  |.|          ||.:        |..|||.|..|.|:.|
Zfish   168 TSGQ-----CEAPLV---KTDI--QAS----------WYKD--------VEGCGIQCDNPLFTED 204

  Fly   313 EKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERF-KYPERPIVFLSACYFMVAVGYLSRNFLQ-- 374
            |......:||::..:....|..||.||:.|.:.. :||...:.:::||:|:.::|:|:: |:.
Zfish   205 EHSDMHSYIAVFGTITLLCTFFTLATFLADWKNSNRYPAVILFYVNACFFIGSIGWLAQ-FMDGA 268

  Fly   375 NEEIAC---DGLLLRE-SSTGPHSCTLVFLLTYFFGMASSIWWVILSFTW---FLAAGLKWGNEA 432
            ..||.|   :.:.|.| |||...||.::|::.|:..|:..||:|:|::.|   |.|.|..  ::.
Zfish   269 RNEIVCKSDNTMRLGEPSSTETLSCVIIFVIVYYSLMSGVIWFVMLTYAWHTSFKALGTT--HQP 331

  Fly   433 ITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTT 497
            ::..:.||||..|.||.:.:||:|..|.||.|.:.|||:||....::...|||||:...||||..
Zfish   332 LSGKTSYFHLVTWSIPFILTVAILANSQVDADSVSGICFVGYRYYEYRAGFVLAPIGFVLVIGGY 396

  Fly   498 FLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFED 562
            ||:.|.::||.|:|   ...|:.:...|.|:.:.|:|:|||..|......|..||:.|:.....:
Zfish   397 FLIRGVMTLFSIKS---NHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFGCHFYDFFNQAE 458

  Fly   563 WIKA----LAC--------------PCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKT 609
            |.::    :.|              |...:|   .:|...|..:..|.....||....|:|:..|
Zfish   459 WERSFREYVLCEANVTIAHQTNKPIPECAIK---NRPSLLVGKINLFSMFGTGIAMSTWVWTKAT 520

  Fly   610 LESWRRFWRRLLGAPD 625
            :..|:|.|.|::|..|
Zfish   521 ILIWKRTWFRIIGRSD 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fz2	NP_001262037.1	CRD_FZ5_like	63..182	CDD:143565	31/125 (25%)
		Frizzled	308..618	CDD:279827	102/337 (30%)
smo	NP_571102.2	CRD_SMO	44..175	CDD:143560	38/206 (18%)
		Frizzled	200..528	CDD:279827	102/336 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D509772at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820