DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz2 and Frzb

DIOPT Version :9

Sequence 1:	NP_001262037.1	Gene:	fz2 / 40090	FlyBaseID:	FBgn0016797	Length:	806	Species:	Drosophila melanogaster
Sequence 2:	NP_001093997.1	Gene:	Frzb / 295691	RGDID:	1311315	Length:	323	Species:	Rattus norvegicus

Alignment Length:	211	Identity:	76/211 - (36%)
Similarity:	104/211 - (49%)	Gaps:	37/211 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GMGGMGMGGHGLDASPAPGYGVPVIPKDPNLRCEEITIPMCRGIGYNMTSFPNEMNHETQDEAGL 96
            |.|.|.:|..||....|  ..:..:|......||.:.||:|:.:.:|||..||.::|.||..|.|
  Rat     5 GPGRMLLGWAGLLVLAA--LCLLQVPGAQAAACEPVRIPLCKSLPWNMTKMPNHLHHSTQANAIL 67

  Fly    97 EVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDY-HKPLPVCRSVCERARSGCAPIMQQYSFEWPE 160
            .:.||..|:...|||||.||||:||.|||..|: |:|:..|:|||||||.||.||:.:|...|||
  Rat    68 AIEQFEGLLGTHCSPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGCEPILIKYRHSWPE 132

  Fly   161 RMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSG 225
            .:|||.||::  ...:|:...:...|                               .||.....
  Rat   133 SLACEELPVY--DRGVCISPEAIVTA-------------------------------DGADFPMD 164

  Fly   226 STSTKPCRGRNSKNCQ 241
            | ||..|||.:|:.|:
  Rat   165 S-STGHCRGTSSERCK 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz2	NP_001262037.1	CRD_FZ5_like	63..182	CDD:143565	57/119 (48%)
fz2	NP_001262037.1	Frizzled	308..618	CDD:279827
Frzb	NP_001093997.1	CRD_SFRP3	32..157	CDD:143550	58/157 (37%)
Frzb	NP_001093997.1	NTR_Sfrp3_like	188..297	CDD:239636
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334865
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11309
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840