DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz2 and Mfrp

DIOPT Version :9

Sequence 1:	NP_001262037.1	Gene:	fz2 / 40090	FlyBaseID:	FBgn0016797	Length:	806	Species:	Drosophila melanogaster
Sequence 2:	NP_667337.1	Gene:	Mfrp / 259172	MGIID:	2385957	Length:	584	Species:	Mus musculus

Alignment Length:	111	Identity:	37/111 - (33%)
Similarity:	51/111 - (45%)	Gaps:	4/111 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 PNLRCEEITIPMCRGIGYNMTSFPN-EMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTP 123
            |:|.||.:.:.||.|:.||.|:||| .:...||.|....:..:..|..:.|....:.|||.:..|
Mouse   467 PDLTCEPVQVEMCLGLSYNTTAFPNIWVGLATQTEVTDILRGYKSLTSLPCYQTFQRFLCGLLVP 531

  Fly   124 ICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPL 169
            .| ......||.|||||:.|...|...:......||  ..|..||:
Mouse   532 RC-TSLGTILPPCRSVCQAAEQQCQSSLALLGTPWP--FNCNRLPV 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz2	NP_001262037.1	CRD_FZ5_like	63..182	CDD:143565	35/108 (32%)
fz2	NP_001262037.1	Frizzled	308..618	CDD:279827
Mfrp	NP_667337.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	108..140
		CUB	150..258	CDD:238001
		LDLa	266..300	CDD:238060
		CUB	307..419	CDD:238001
		Fz	471..573	CDD:279700	33/104 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900