Protein Alignment fz2 and FRZB

DIOPT Version :9

• Sequence 1: NP_001262037.1
• Gene: fz2 / 40090
• FlyBaseID: FBgn0016797
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_001454.2
• Gene: FRZB / 2487
• HGNCID: 3959
• Length: 325
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 86/289 - (29%)
• Similarity: 122/289 - (42%)
• Gaps: 66/289 - (22%)

  Fly    64 CEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLED 128
            ||.:.||:|:.:.:|||..||.::|.||..|.|.:.||..|:...|||||.||||:||.|||..|
Human    35 CEPVRIPLCKSLPWNMTKMPNHLHHSTQANAILAIEQFEGLLGTHCSPDLLFFLCAMYAPICTID 99

  Fly   129 Y-HKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSS 192
            : |:|:..|:|||||||.||.||:.:|...|||.:|||.||::  ...:|:...:...|......
Human   100 FQHEPIKPCKSVCERARQGCEPILIKYRHSWPENLACEELPVY--DRGVCISPEAIVTADGADFP 162

  Fly   193 GGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGE--KASGKECSC 255
            ..|                   |.|:..|.||.....||.|.......:|....  :|..||...
Human   163 MDS-------------------SNGNCRGASSERCKCKPIRATQKTYFRNNYNYVIRAKVKEIKT 208

  Fly   256 SCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLW 320
            .|......:..:::|:..                    :..:|               :|...|:
Human   209 KCHDVTAVVEVKEILKSS--------------------LVNIP---------------RDTVNLY 238

  Fly   321 IALWSGLCFCSTLMTLTTFII----DTER 345
            .:  || |.|..|.....:||    |.||
Human   239 TS--SG-CLCPPLNVNEEYIIMGYEDEER 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fz2	NP_001262037.1	CRD_FZ5_like	63..182	CDD:143565	57/118 (48%)
		Frizzled	308..618	CDD:279827	12/42 (29%)
FRZB	NP_001454.2	CRD_SFRP3	32..157	CDD:143550	57/123 (46%)
		NTR_Sfrp3_like	188..297	CDD:239636	19/115 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..325

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141199
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11309
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840